Interactor 1: ARRB2 (P32121)
Beta-arrestin-2 (Arrestin beta-2) (Non-visual arrestin-3)
Gene: ARRB2

Interactor 2: FFAR4 (Q5NUL3)
Free fatty acid receptor 4 (G-protein coupled receptor 120) (G-protein coupled receptor 129) (G-protein coupled receptor GT01) (G-protein coupled receptor PGR4) (Omega-3 fatty acid receptor 1)
Gene: FFAR4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.34 1.00 0.590

The method score is based on:

Property Details
Experiments 22282525
Identification Methods bimolecular fluorescence complementation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~Arrestin_C, 7tm_1~Arrestin_N
Common GO terms GO:0005886 - plasma membrane
GO:0030139 - endocytic vesicle
GO:0032691 - negative regulation of interleukin-1 beta production
GO:0070374 - positive regulation of ERK1 and ERK2 cascade
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 409
Hs

1 361
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024