Protein: DBF2
Cell cycle protein kinase DBF2 (EC 2.7.11.1) (Dumbbell forming protein 2)

Gene: DBF2
Organism: Saccharomyces cerevisiae S288C
Interactions: 186
UniProt ID: P22204

Gene Ontology (top 5):
GO:0000280 - nuclear division
GO:0003723 - RNA binding
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

605573

CDC14
Tyrosine-protein phosphatase CDC14

3

10

Small-scale

0.857

High

605491

CDC15
Cell division control protein 15

2

20

Small-scale

0.806

High

605485

CG23
G2/mitotic-specific cyclin-3

2

7

Small-scale

0.789

High

605514

KKQ8
Probable serine/threonine-protein kinase KKQ8

2

17

Small-scale

0.778

High

605567

FPK1
Flippase kinase 1

2

18

Small-scale

0.778

High

605585

RRP5
rRNA biogenesis protein RRP5

2

5

Small-scale

0.778

High

605597

YP150
Putative serine/threonine-protein kinase YPL150W

2

9

Small-scale

0.778

High

605604

OSH2
Oxysterol-binding protein homolog 2

2

2

Small-scale

0.778

High

605543

MOB1
DBF2 kinase activator protein MOB1

12

20

Small-scale

0.763

High

605533

SSN3
Meiotic mRNA stability protein kinase SSN3

1

17

Small-scale

0.740

High

339439

CDK1
Cyclin-dependent kinase 1

1

11

High-throughput

0.724

High

419802

SNF1
Carbon catabolite-derepressing protein kinase

1

6

High-throughput

0.691

High

443922

CYAA
Adenylate cyclase

1

10

High-throughput

0.691

High

520577

YPK1
Serine/threonine-protein kinase YPK1

1

17

High-throughput

0.691

High

605497

CCR4
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4

3

3

Small-scale

0.685

High

605486

SIS1
Protein SIS1

1

7

High-throughput

0.647

High

365804

HSP82
ATP-dependent molecular chaperone HSP82

1

20

High-throughput

0.646

High

543211

HSC82
ATP-dependent molecular chaperone HSC82

1

20

High-throughput

0.646

High

605502

RPN2
26S proteasome regulatory subunit RPN2

1

3

High-throughput

0.646

High

605532

POP2
Poly(A) ribonuclease POP2

3

0

Small-scale

0.622

High

605480

DBF2
Cell cycle protein kinase DBF2

1

18

High-throughput

0.618

High

605484

CG22
G2/mitotic-specific cyclin-2

1

7

Small-scale

0.618

High

605531

TEM1
Protein TEM1

1

9

High-throughput

0.618

High

605575

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

11

High-throughput

0.618

High

421750

KAD2
Adenylate kinase

2

3

Small-scale

0.602

High

597196

PSA7
Probable proteasome subunit alpha type-7

2

1

Small-scale

0.602

High

605503

PAH1
Phosphatidic acid phosphohydrolase 1

2

2

Small-scale

0.602

High

605569

CUZ1
CDC48-associated ubiquitin-like/zinc finger protein 1

2

1

Small-scale

0.602

High

605554

SYEC
Glutamate--tRNA ligase, cytoplasmic

2

3

High-throughput

0.602

High

605606

RUVB2
RuvB-like protein 2

2

5

High-throughput

0.594

High

605522

HMT1
Protein arginine N-methyltransferase 1

1

4

Small-scale

0.589

High

454182

TBA1
Tubulin alpha-1 chain

2

7

High-throughput

0.584

High

605579

RNT1
Ribonuclease 3

2

0

Small-scale

0.577

High

605511

HSP78
Heat shock protein 78, mitochondrial

2

4

High-throughput

0.571

High

360739

TBB
Tubulin beta chain

2

10

High-throughput

0.565

High

605492

BUD14
Bud site selection protein 14

2

0

High-throughput

0.561

High

605499

NUD1
Protein NUD1

1

13

High-throughput

0.553

High

493217

HSP72
Heat shock protein SSA2

2

15

High-throughput

0.552

High

605539

SSB2
Ribosome-associated molecular chaperone SSB2

2

14

High-throughput

0.552

High

367744

EF1A
Elongation factor 1-alpha

2

4

Small-scale

0.550

High

605526

AIM3
Altered inheritance of mitochondria protein 3

2

11

Small-scale

0.550

High

605529

YB8A
Putative uncharacterized protein YBR285W

2

1

Small-scale

0.550

High

605541

VPS27
Vacuolar protein sorting-associated protein 27

2

5

Small-scale

0.550

High

605542

VHS2
Protein VHS2

2

1

Small-scale

0.550

High

605561

AVT4
Vacuolar amino acid transporter 4

2

1

Small-scale

0.550

High

605580

ADD37
Alpha1-proteinase inhibitor-degradation deficient protein 37

2

1

Small-scale

0.550

High

605588

NVJ2
Nucleus-vacuole junction protein 2

2

1

Small-scale

0.550

High

605601

HSP42
Heat shock protein 42

2

2

High-throughput

0.549

High

566525

VATA
V-type proton ATPase catalytic subunit A

1

13

High-throughput

0.536

High

605494

LCF1
Long-chain-fatty-acid--CoA ligase 1

1

3

High-throughput

0.536

High

605495

XPO1
Exportin-1

1

8

High-throughput

0.536

High

605498

PROB
Glutamate 5-kinase

1

2

High-throughput

0.536

High

605508

PRS6A
26S proteasome regulatory subunit 6A

1

10

High-throughput

0.536

High

605509

PRS6B
26S proteasome regulatory subunit 6B homolog

1

8

High-throughput

0.536

High

605545

MKT1
Post-transcriptional regulator MKT1

1

1

High-throughput

0.536

High

605546

SA185
SIT4-associating protein SAP185

1

2

High-throughput

0.536

High

605563

PNC1
Nicotinamidase

1

1

High-throughput

0.536

High

605584

EMI2
Putative glucokinase-2

1

3

High-throughput

0.536

High

434517

OAT
Ornithine aminotransferase

1

0

High-throughput

0.513

High

605560

RIB4
6,7-dimethyl-8-ribityllumazine synthase

1

0

High-throughput

0.513

High

605568

CAF40
Protein CAF40

1

1

Small-scale

0.508

High

605518

CAF4
CCR4-associated factor 4

1

17

Small-scale

0.504

High

343803

SYMC
Methionine--tRNA ligase, cytoplasmic

1

6

High-throughput

0.501

High

356254

H4
Histone H4

1

3

Small-scale

0.501

High

482552

YA11A
Transposon Ty1-A Gag polyprotein

1

3

High-throughput

0.501

High

482613

YE11A
Transposon Ty1-ER1 Gag polyprotein

1

3

High-throughput

0.501

High

563921

SEC2
Rab guanine nucleotide exchange factor SEC2

1

1

High-throughput

0.501

High

565143

CBF1
Centromere-binding protein 1

1

2

Small-scale

0.501

High

605483

SSD1
Protein SSD1

1

3

High-throughput

0.501

High

605507

DRS1
ATP-dependent RNA helicase DRS1

1

13

High-throughput

0.501

High

605524

SRO77
Lethal(2) giant larvae protein homolog SRO77

1

2

High-throughput

0.501

High

605525

NCL1
Multisite-specific tRNA:(cytosine-C(5))-methyltransferase

1

3

High-throughput

0.501

High

605538

BUD16
Putative pyridoxal kinase BUD16

1

2

High-throughput

0.501

High

605550

ELP2
Elongator complex protein 2

1

11

High-throughput

0.501

High

605565

H1
Histone H1

1

1

Small-scale

0.501

High

605577

MTD1
Methylenetetrahydrofolate dehydrogenase [NAD(+)]

1

1

High-throughput

0.501

High

605581

NHP10
Non-histone protein 10

1

10

High-throughput

0.501

High

605586

CYK2
Cytokinesis protein 2

1

2

Small-scale

0.501

High

605589

BDF2
Bromodomain-containing factor 2

1

8

High-throughput

0.501

High

605595

SAS10
Something about silencing protein 10

1

2

High-throughput

0.501

High

605602

NDJ1
Non-disjunction protein 1

1

1

High-throughput

0.501

High

605603

YN11A
Transposon Ty1-NL1 Gag polyprotein

1

3

High-throughput

0.501

High

605607

YG12A
Transposon Ty1-GR2 Gag polyprotein

1

3

High-throughput

0.501

High

605608

H2AZ
Histone H2A.Z

1

12

Small-scale

0.501

High

341925

ATPB
ATP synthase subunit beta, mitochondrial

1

10

High-throughput

0.500

High

389223

HXKA
Hexokinase-1

1

3

High-throughput

0.500

High

423761

ATPA
ATP synthase subunit alpha, mitochondrial

1

11

High-throughput

0.500

High

424345

PYR1
Multifunctional protein URA2

1

6

High-throughput

0.500

High

439972

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

5

High-throughput

0.500

High

449911

HSP73
Heat shock protein SSA3

1

15

High-throughput

0.500

High

498440

METK1
S-adenosylmethionine synthase 1

1

3

High-throughput

0.500

High

554556

HSP26
Heat shock protein 26

1

2

High-throughput

0.500

High

562320

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

9

High-throughput

0.500

High

605592

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

2

High-throughput

0.500

High

343272

TRPG
Multifunctional tryptophan biosynthesis protein [Includes: Anthranilate synthase component 2

1

7

High-throughput

0.489

High

417560

PHSG
Glycogen phosphorylase

1

4

High-throughput

0.489

High

540026

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

2

High-throughput

0.489

High

546684

SEC23
Protein transport protein SEC23

1

2

High-throughput

0.489

High

605520

GLYC
Serine hydroxymethyltransferase, cytosolic

1

1

High-throughput

0.489

High

605548

COPB2
Coatomer subunit beta'

1

6

High-throughput

0.489

High

605599

RPN5
26S proteasome regulatory subunit RPN5

1

1

High-throughput

0.489

High

605600

IQG1
Ras GTPase-activating-like protein IQG1

1

11

High-throughput

0.481

High

535978

CHS2
Chitin synthase 2

1

0

Small-scale

0.480

High

605517

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.480

High

605519

YK21
Uncharacterized protein YKR041W

1

0

High-throughput

0.480

High

605536

OAF1
Oleate-activated transcription factor 1

1

0

Small-scale

0.480

High

605566

TR112
Multifunctional methyltransferase subunit TRM112

1

0

High-throughput

0.480

High

605591

NSE1
Non-structural maintenance of chromosomes element 1

1

0

High-throughput

0.480

High

424814

IF4E
Eukaryotic translation initiation factor 4E

1

2

High-throughput

0.479

High

605482

SPA2
Protein SPA2

1

12

High-throughput

0.479

High

605490

AP2B
AP-2 complex subunit beta

1

5

High-throughput

0.479

High

605493

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

605510

SEC3
Exocyst complex component SEC3

1

20

High-throughput

0.479

High

605513

SKI2
Antiviral helicase SKI2

1

12

High-throughput

0.479

High

605549

GPD2
Glycerol-3-phosphate dehydrogenase [NAD(+)] 2, mitochondrial

1

1

High-throughput

0.479

High

605552

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

4

High-throughput

0.479

High

605571

H3
Histone H3

1

8

High-throughput

0.479

High

605596

RRP6
Exosome complex exonuclease RRP6

1

1

High-throughput

0.479

High

605598

RIO1
Serine/threonine-protein kinase RIO1

1

2

High-throughput

0.479

High

409821

NOT2
General negative regulator of transcription subunit 2

1

0

Small-scale

0.460

High

605562

TAN1
tRNA acetyltransferase TAN1

1

0

High-throughput

0.458

High

605564

YG1T
Uncharacterized protein YGR042W

1

0

High-throughput

0.458

High

479064

RL43B
Large ribosomal subunit protein eL43B

1

1

High-throughput

0.457

High

546507

AMPD
AMP deaminase

1

2

High-throughput

0.457

High

605488

ADH7
NADP-dependent alcohol dehydrogenase 7

1

1

High-throughput

0.457

High

605496

RM09
Large ribosomal subunit protein uL3m

1

3

High-throughput

0.457

High

605515

AVT3
Vacuolar amino acid transporter 3

1

1

High-throughput

0.457

High

605528

MCFS2
Medium-chain fatty acid ethyl ester synthase/esterase 2

1

2

High-throughput

0.457

High

605555

ARC1
tRNA-aminoacylation cofactor ARC1

1

1

High-throughput

0.457

High

605559

HSV2
SVP1-like protein 2

1

8

High-throughput

0.457

High

605570

ESBP6
Uncharacterized transporter ESBP6

1

4

High-throughput

0.457

High

605582

YMD7
Uncharacterized protein YML037C

1

1

High-throughput

0.457

High

605587

BFR2
Protein BFR2

1

1

High-throughput

0.457

High

343535

PMG1
Phosphoglycerate mutase 1

1

6

High-throughput

0.457

High

397575

OTC
Ornithine carbamoyltransferase

1

6

High-throughput

0.457

High

421573

FAS1
Fatty acid synthase subunit beta

1

3

High-throughput

0.457

High

520788

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

4

High-throughput

0.457

High

581262

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

4

High-throughput

0.457

High

604349

CLH
Clathrin heavy chain

1

4

High-throughput

0.457

High

340024

KPYK1
Pyruvate kinase 1

1

1

High-throughput

0.445

High

477908

HSP77
Import motor subunit, mitochondrial

1

15

High-throughput

0.445

High

490358

HSP71
Heat shock protein SSA1

1

15

High-throughput

0.445

High

510279

SSB1
Ribosome-associated molecular chaperone SSB1

1

14

High-throughput

0.445

High

555815

VATB
V-type proton ATPase subunit B

1

11

High-throughput

0.445

High

605504

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

605505

HSP79
Heat shock protein homolog SSE2

1

20

High-throughput

0.445

High

605523

ADH5
Alcohol dehydrogenase 5

1

1

High-throughput

0.445

High

605534

TCPB
T-complex protein 1 subunit beta

1

11

High-throughput

0.445

High

605572

GPD1
Glycerol-3-phosphate dehydrogenase [NAD(+)] 1

1

1

High-throughput

0.445

High

605487

BPH1
Beige protein homolog 1

1

11

High-throughput

0.437

High

605500

HXT1
Low-affinity glucose transporter HXT1

1

1

High-throughput

0.437

High

605501

NUP2
Nucleoporin NUP2

1

7

High-throughput

0.437

High

605535

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.437

High

605544

AIM21
Altered inheritance of mitochondria protein 21

1

8

High-throughput

0.437

High

605576

MAP1
Methionine aminopeptidase 1

1

3

High-throughput

0.437

High

605578

UTP6
U3 small nucleolar RNA-associated protein 6

1

2

High-throughput

0.437

High

605593

AP3D
AP-3 complex subunit delta

1

6

High-throughput

0.437

High

605605

SPSY
Spermine synthase SPE4

1

1

High-throughput

0.437

High

605537

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

12

High-throughput

0.407

High

605556

NET1
Nucleolar protein NET1

4

0

Small-scale

0.361

High

605506

CDC13
Cell division control protein 13

2

0

Small-scale

0.314

High

605527

YBY8
Uncharacterized protein YBR138C

2

0

Small-scale

0.314

High

605551

PRM10
Pheromone-regulated membrane protein 10

2

0

Small-scale

0.314

High

509183

G6PD
Glucose-6-phosphate 1-dehydrogenase

1

0

High-throughput

0.279

Low

524170

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.279

Low

605489

ILV6
Acetolactate synthase small subunit, mitochondrial

1

0

High-throughput

0.279

Low

605521

GLY1
Low specificity L-threonine aldolase

1

0

High-throughput

0.279

Low

605557

GPN1
GPN-loop GTPase 1

1

0

High-throughput

0.279

Low

605574

TPS1
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit

1

0

High-throughput

0.279

Low

333361

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

1

0

High-throughput

0.261

Low

410485

CYSD
Homocysteine/cysteine synthase

1

0

High-throughput

0.261

Low

605481

AIM17
Probable oxidoreductase AIM17

1

0

High-throughput

0.261

Low

605512

TGL1
Sterol esterase TGL1

1

0

High-throughput

0.261

Low

605516

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

0

High-throughput

0.261

Low

605530

YHY2
Uncharacterized protein YHR182W

1

0

High-throughput

0.261

Low

605547

YJV3
Uncharacterized protein YJL213W

1

0

High-throughput

0.261

Low

605558

YJ9J
Uncharacterized protein YJR142W

1

0

High-throughput

0.261

Low

605583

YM54
Uncharacterized protein YMR196W

1

0

High-throughput

0.261

Low

605594

MCP1
Mitochondrial adapter protein MCP1

1

0

High-throughput

0.261

Low

404302

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

0

High-throughput

0.261

Low

452958

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.261

Low

520912

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.261

Low

605553

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

0

High-throughput

0.261

Low

605540

DOA10
ERAD-associated E3 ubiquitin-protein ligase DOA10

1

0

High-throughput

0.249

Low

605590

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024