HitPredict

Interactor 1: CCR1 (P32246)
C-C chemokine receptor type 1 (C-C CKR-1) (CC-CKR-1) (CCR-1) (CCR1) (HM145) (LD78 receptor) (Macrophage inflammatory protein 1-alpha receptor) (MIP-1alpha-R) (RANTES-R) (CD antigen CD191)
Gene: CCR1

Interactor 2: CCL7 (P80098)
C-C motif chemokine 7 (Monocyte chemoattractant protein 3) (Monocyte chemotactic protein 3) (MCP-3) (NC28) (Small-inducible cytokine A7)
Gene: CCL7

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.899

The method score is based on:

Property Details
Experiments 8530354, 7545673, 9336350, 12381680
Identification Methods pull down, experimental interaction detection, biochemical, competition binding
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~IL8
Common GO terms GO:0006874 - intracellular calcium ion homeostasis
GO:0006935 - chemotaxis
GO:0006954 - inflammatory response
GO:0007267 - cell-cell signaling
GO:0030335 - positive regulation of cell migration
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 355
Hs

1 99
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024