Protein: GTPB3
5-taurinomethyluridine-[tRNA] synthase subunit GTPB3, mitochondrial (EC 3.6.1.-) (GTP-binding protein 3) (Mitochondrial GTP-binding protein 1) (tRNA modification GTPase GTPBP3, mitochondrial)

Gene: GTPB3, GTPBP3
Organism: Homo sapiens
Interactions: 88
UniProt ID: Q969Y2

Gene Ontology (top 5):
GO:0002098 - tRNA wobble uridine modification
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1381628

GTPB3
5-taurinomethyluridine-[tRNA] synthase subunit GTPB3, mitochondrial

2

17

High-throughput

0.815

High

1381644

PAR11
Protein mono-ADP-ribosyltransferase PARP11

3

4

High-throughput

0.667

High

212465

SPIT2
Kunitz-type protease inhibitor 2

3

4

High-throughput

0.667

High

856325

IF2M
Translation initiation factor IF-2, mitochondrial

1

12

High-throughput

0.618

High

882808

EFTU
Elongation factor Tu, mitochondrial

1

8

High-throughput

0.618

High

1381636

MTG1
Mitochondrial ribosome-associated GTPase 1

1

8

High-throughput

0.618

High

1381640

MTG2
Mitochondrial ribosome-associated GTPase 2

1

15

High-throughput

0.618

High

635092

CAN3
Calpain-3

2

1

High-throughput

0.606

High

1103013

CENPR
Centromere protein R

2

1

High-throughput

0.606

High

1239722

PPR18
Phostensin

2

2

High-throughput

0.606

High

1370276

CSN5
COP9 signalosome complex subunit 5

2

4

High-throughput

0.606

High

279848

CISY
Citrate synthase, mitochondrial

2

4

High-throughput

0.584

High

1162465

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

3

High-throughput

0.584

High

1081432

INCA1
Protein INCA1

2

0

High-throughput

0.580

High

1239192

ZN774
Zinc finger protein 774

2

0

High-throughput

0.580

High

1271197

DPPA4
Developmental pluripotency-associated protein 4

2

0

High-throughput

0.580

High

1353567

ZFP90
Zinc finger protein 90 homolog

2

0

High-throughput

0.580

High

1359972

MB3L1
Methyl-CpG-binding domain protein 3-like 1

2

0

High-throughput

0.580

High

1381648

ZNF69
Zinc finger protein 69

2

0

High-throughput

0.580

High

1381651

SRTD3
SERTA domain-containing protein 3

2

0

High-throughput

0.580

High

640252

EPHA1
Ephrin type-A receptor 1

2

10

High-throughput

0.574

High

1090270

ELAV2
ELAV-like protein 2

2

2

High-throughput

0.574

High

572326

CBPM
Carboxypeptidase M

2

2

High-throughput

0.558

High

1231575

TBC3G
TBC1 domain family member 3G

2

9

High-throughput

0.553

High

215163

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

1

1

High-throughput

0.541

High

1215345

DCAF8
DDB1- and CUL4-associated factor 8

1

8

High-throughput

0.541

High

1381632

CIC
Protein capicua homolog

1

7

High-throughput

0.541

High

260785

RAMP2
Receptor activity-modifying protein 2

1

1

High-throughput

0.536

High

690526

KAD4
Adenylate kinase 4, mitochondrial

1

1

High-throughput

0.536

High

733970

P5CR1
Pyrroline-5-carboxylate reductase 1, mitochondrial

1

2

High-throughput

0.536

High

1275804

RM21
Large ribosomal subunit protein bL21m

1

3

High-throughput

0.536

High

1381633

RSLAB
Ras-like protein family member 10B

1

19

High-throughput

0.536

High

1381655

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

4

High-throughput

0.536

High

1381639

RIBC2
RIB43A-like with coiled-coils protein 2

1

0

High-throughput

0.518

High

1381643

SHCAF
SIN3-HDAC complex-associated factor

1

0

High-throughput

0.518

High

1096147

TADBP
TAR DNA-binding protein 43

1

3

High-throughput

0.515

High

1232505

Q6FHY5
MEOX2 protein

1

4

High-throughput

0.515

High

1381635

HTF4
Transcription factor 12

1

1

High-throughput

0.515

High

1234685

ETFR1
Electron transfer flavoprotein regulatory factor 1

1

0

High-throughput

0.513

High

185910

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

4

High-throughput

0.501

High

669281

PTAFR
Platelet-activating factor receptor

1

2

High-throughput

0.494

High

1381630

DDT4L
DNA damage-inducible transcript 4-like protein

1

0

High-throughput

0.493

High

133292

P2Y10
Putative P2Y purinoceptor 10

1

3

High-throughput

0.489

High

1249824

BTNL9
Butyrophilin-like protein 9

1

6

High-throughput

0.489

High

1381656

GPR45
Probable G-protein coupled receptor 45

1

1

High-throughput

0.489

High

894077

MEOX2
Homeobox protein MOX-2

1

4

High-throughput

0.481

High

1381638

PDIP3
Polymerase delta-interacting protein 3

1

5

High-throughput

0.481

High

1381652

RALY
RNA-binding protein Raly

1

2

High-throughput

0.481

High

242515

PRKN
E3 ubiquitin-protein ligase parkin

1

11

High-throughput

0.479

High

282029

MPPB
Mitochondrial-processing peptidase subunit beta

1

7

High-throughput

0.479

High

294130

CD123
Translation initiation factor eIF2 assembly protein

1

4

High-throughput

0.479

High

350939

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

4

High-throughput

0.479

High

463695

LYN
Tyrosine-protein kinase Lyn

1

3

Small-scale

0.479

High

519184

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

2

High-throughput

0.479

High

560037

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

2

High-throughput

0.479

High

828878

MDHM
Malate dehydrogenase, mitochondrial

1

7

High-throughput

0.479

High

851973

EFTS
Elongation factor Ts, mitochondrial

1

3

High-throughput

0.479

High

1113929

CUL3
Cullin-3

1

5

High-throughput

0.479

High

1117795

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

7

High-throughput

0.479

High

1142615

PDK1
[Pyruvate dehydrogenase

1

3

High-throughput

0.479

High

1234475

MRM1
rRNA methyltransferase 1, mitochondrial

1

3

High-throughput

0.479

High

1381629

MCUR1
Mitochondrial calcium uniporter regulator 1

1

2

High-throughput

0.479

High

1381631

RRFM
Ribosome-recycling factor, mitochondrial

1

3

High-throughput

0.479

High

1381634

IMP2L
Mitochondrial inner membrane protease subunit 2

1

3

High-throughput

0.479

High

1381641

MET17
Ribosome assembly protein METTL17, mitochondrial

1

3

High-throughput

0.479

High

1381642

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

8

High-throughput

0.479

High

1381645

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

6

High-throughput

0.479

High

1381647

MRES1
Mitochondrial transcription rescue factor 1

1

3

High-throughput

0.479

High

1381649

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

11

High-throughput

0.479

High

1381650

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

1381654

FYV1
1-phosphatidylinositol 3-phosphate 5-kinase

1

1

High-throughput

0.470

High

353482

AGR2
Anterior gradient protein 2 homolog

1

4

High-throughput

0.470

High

1145647

RCN1
Reticulocalbin-1

1

4

High-throughput

0.470

High

1199171

Q53GL6
RNA binding protein

1

2

High-throughput

0.470

High

1357108

Q8WUT1
POLDIP3 protein

1

2

High-throughput

0.470

High

653483

HEMH
Ferrochelatase, mitochondrial

1

2

High-throughput

0.445

High

686636

ELAV4
ELAV-like protein 4

1

2

High-throughput

0.445

High

1178293

CL16A
Protein CLEC16A

1

4

High-throughput

0.437

High

379694

IGHA1
Immunoglobulin heavy constant alpha 1

1

3

High-throughput

0.407

High

1131212

MESD
LRP chaperone MESD

2

0

High-throughput

0.316

High

1330671

BEND7
BEN domain-containing protein 7

2

0

High-throughput

0.316

High

1381637

CCD32
Coiled-coil domain-containing protein 32

2

0

High-throughput

0.316

High

608915

PFKAL
ATP-dependent 6-phosphofructokinase, liver type

1

0

High-throughput

0.299

High

1381653

GLCNE
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase

1

0

High-throughput

0.299

High

1272618

PCAT2
Lysophosphatidylcholine acyltransferase 2

1

0

High-throughput

0.279

Low

1381646

KLK14
Kallikrein-14

1

0

High-throughput

0.279

Low

1309395

SPNS2
Sphingosine-1-phosphate transporter SPNS2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025