HitPredict

Interactor 1: FOXN2 (P32314)
Forkhead box protein N2 (Human T-cell leukemia virus enhancer factor)
Gene: FOXN2

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	29396548, 25609649, 28514442, 33961781
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 431 Hs			1 605
+	Hs
		687050 FOXN2_HUMAN (1-431): 2.77e-171: 488: 100.00		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		127127 FOXN3_HUMAN (1-428): 1.78e-101: 312: 42.97		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		127126 FOXN3_HUMAN (1-428): 1.78e-101: 312: 42.97		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		877647 FOXG1_HUMAN (111-217): 2.13e-47: 171: 42.06		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1021177 FOXC1_HUMAN (76-320): 3.95e-46: 169: 19.60		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		993337 FOXM1_HUMAN (33-393): 3.57e-55: 197: 21.36		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Mm
		1158246 Q6P1H7_MOUSE (44-393): 6.64e-51: 185: 21.62		FBXW7_MOUSE (76-527): 2.98e-83: 277: 23.71
+	Hs
		178984 FOXP2_HUMAN (85-364): 9.83e-47: 172: 23.93		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		877671 FOXA1_HUMAN (2-348): 4.85e-60: 204: 22.06		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		245596 FOXI1_HUMAN (8-351): 6.59e-66: 217: 20.23		TBL1X_HUMAN (501-605): 3.8e-15: 80.4: 19.13
+	Hs
		1021159 FOXC1_HUMAN (76-320): 3.95e-46: 169: 19.60		TBL1R_HUMAN (501-605): 3.85e-15: 80.4: 16.67
+	Hs
		245597 FOXL1_HUMAN (87-273): 3.6e-48: 169: 25.39		TBL1X_HUMAN (501-605): 3.8e-15: 80.4: 19.13
+	Hs
		245590 FOXK2_HUMAN (111-220): 3.53e-18: 89: 43.80		TBL1X_HUMAN (501-605): 3.8e-15: 80.4: 19.13
+	Hs
		964245 FOXK2_HUMAN (111-220): 3.53e-18: 89: 43.80		TBL1R_HUMAN (501-605): 3.85e-15: 80.4: 16.67
+	Hs
		952865 FOXK1_HUMAN (111-218): 1.24e-17: 87.4: 42.86		TBL1R_HUMAN (501-605): 3.85e-15: 80.4: 16.67
+	Hs
		964241 FOXK2_HUMAN (111-220): 3.53e-18: 89: 43.80		TBL1Y_HUMAN (501-605): 2.08e-14: 78.1: 20.00