Protein: PPZ1
Serine/threonine-protein phosphatase PP-Z1 (EC 3.1.3.16)

Gene: PPZ1
Organism: Saccharomyces cerevisiae S288C
Interactions: 103
UniProt ID: P26570

Gene Ontology (top 5):
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006883 - intracellular sodium ion homeostasis
GO:0008104 - intracellular protein localization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

687047

SDS22
Protein phosphatase 1 regulatory subunit SDS22

4

20

High-throughput

0.906

High

687062

YPI1
Type 1 phosphatases regulator YPI1

4

3

Small-scale

0.888

High

687039

PPZ2
Serine/threonine-protein phosphatase PP-Z2

3

14

High-throughput

0.852

High

687029

PPZ1
Serine/threonine-protein phosphatase PP-Z1

2

13

High-throughput

0.785

High

687061

GLC8
Protein GLC8

2

2

Small-scale

0.775

High

687045

SIS2
Phosphopantothenoylcysteine decarboxylase subunit SIS2

14

7

Small-scale

0.762

High

687048

CAB3
Coenzyme A biosynthesis protein 3

4

7

High-throughput

0.701

High

687086

VHS3
Phosphopantothenoylcysteine decarboxylase subunit VHS3

4

9

Small-scale

0.643

High

392328

HSP82
ATP-dependent molecular chaperone HSP82

1

3

High-throughput

0.618

High

687041

UBX1
UBX domain-containing protein 1

2

10

Small-scale

0.611

High

663307

FPS1
Glycerol uptake/efflux facilitator protein

2

0

High-throughput

0.587

High

687063

STE24
CAAX prenyl protease 1

2

0

High-throughput

0.587

High

687055

GIP2
GLC7-interacting protein 2

1

20

Small-scale

0.587

High

687035

PP12
Serine/threonine-protein phosphatase PP1-2

1

14

High-throughput

0.575

High

687084

FKBP4
FK506-binding protein 4

1

3

High-throughput

0.575

High

687067

ERG25
C-4 methylsterol oxidase ERG25

2

2

High-throughput

0.559

High

523220

HSP71
Heat shock protein SSA1

2

17

High-throughput

0.552

High

609266

CPT1
Cholinephosphotransferase 1

1

1

High-throughput

0.541

High

687090

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

1

High-throughput

0.541

High

544010

SSB1
Ribosome-associated molecular chaperone SSB1

1

17

High-throughput

0.536

High

687032

XPO1
Exportin-1

1

3

High-throughput

0.536

High

687033

IMPX
Sugar utilization regulatory protein IMP2

1

1

High-throughput

0.536

High

687074

HAL1
Halotolerance protein HAL1

1

1

High-throughput

0.536

High

439507

PIS
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

1

0

High-throughput

0.518

High

561183

PYRE
Orotate phosphoribosyltransferase 1

1

0

High-throughput

0.518

High

687058

VHS2
Protein VHS2

1

0

High-throughput

0.518

High

687083

PLM2
Protein PLM2

1

0

High-throughput

0.518

High

687093

PST2
Protoplast secreted protein 2

1

0

High-throughput

0.518

High

687054

RV167
Reduced viability upon starvation protein 167

1

4

High-throughput

0.515

High

687095

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.513

High

687042

SCD5
Protein SCD5

1

1

Small-scale

0.508

High

687057

TBP6
Probable 26S proteasome subunit YTA6

1

9

Small-scale

0.508

High

687073

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

1

10

High-throughput

0.508

High

602341

PHO85
Cyclin-dependent protein kinase PHO85

1

13

High-throughput

0.501

High

367708

ENO1
Enolase 1

1

2

High-throughput

0.500

High

439266

PDC1
Pyruvate decarboxylase isozyme 1

1

4

High-throughput

0.500

High

597056

BIP
Endoplasmic reticulum chaperone BiP

1

14

High-throughput

0.500

High

625879

HNM1
Choline transporter

1

2

High-throughput

0.494

High

687046

MID2
Cell wall integrity sensor MID2

1

8

High-throughput

0.494

High

687052

SUR2
Sphingolipid C4-hydroxylase SUR2

1

2

High-throughput

0.494

High

687066

MUP1
High-affinity methionine permease

1

2

High-throughput

0.494

High

661587

MPCP
Mitochondrial phosphate carrier protein

1

4

High-throughput

0.489

High

687080

JIP4
Uncharacterized protein JIP4

1

2

High-throughput

0.489

High

687036

RU1A
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.486

High

623783

MYO2
Myosin-2

1

9

Small-scale

0.481

High

646317

RAD53
Serine/threonine-protein kinase RAD53

1

7

Small-scale

0.481

High

687037

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

5

Small-scale

0.481

High

687094

MPC70
Sporulation-specific protein 21

1

1

Small-scale

0.481

High

434875

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.479

High

674454

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.479

High

679431

CDC48
Cell division control protein 48

1

7

High-throughput

0.479

High

687030

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

687031

BMH1
Protein BMH1

1

8

High-throughput

0.479

High

687044

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

687049

GBLP
Small ribosomal subunit protein RACK1

1

10

High-throughput

0.479

High

687059

ULP2
Ubiquitin-like-specific protease 2

1

2

High-throughput

0.479

High

687060

DSN1
Kinetochore-associated protein DSN1

1

3

High-throughput

0.479

High

687064

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.479

High

687082

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

687085

VAM6
Vacuolar morphogenesis protein 6

1

5

High-throughput

0.479

High

687087

SGO1
Shugoshin

1

1

High-throughput

0.479

High

687092

SMT3
Ubiquitin-like protein SMT3

1

1

High-throughput

0.479

High

687097

LAS17
Proline-rich protein LAS17

1

4

Small-scale

0.479

High

479670

F16P
Fructose-1,6-bisphosphatase

1

0

Small-scale

0.458

High

687038

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

687040

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.458

High

622886

CSK22
Casein kinase II subunit alpha'

1

15

High-throughput

0.457

High

687068

YG3A
Uncharacterized protein YGR130C

1

20

High-throughput

0.457

High

687075

OSH6
Oxysterol-binding protein homolog 6

1

2

High-throughput

0.457

High

687096

RTN2
Reticulon-like protein 2

1

2

High-throughput

0.457

High

405047

LEU3
3-isopropylmalate dehydrogenase

1

1

High-throughput

0.457

High

456350

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

4

High-throughput

0.457

High

626622

HSP60
Heat shock protein 60, mitochondrial

1

6

High-throughput

0.457

High

510252

HSP77
Import motor subunit, mitochondrial

1

15

High-throughput

0.445

High

526060

HSP72
Heat shock protein SSA2

1

17

High-throughput

0.445

High

687056

SSB2
Ribosome-associated molecular chaperone SSB2

1

17

High-throughput

0.445

High

687072

SEN1
Helicase SEN1

1

5

Small-scale

0.445

High

571307

RED1
Protein RED1

1

1

Small-scale

0.439

High

687053

PCF11
Protein PCF11

1

0

High-throughput

0.438

High

383553

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.437

High

687050

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

687065

TOM22
Mitochondrial import receptor subunit TOM22

1

1

High-throughput

0.437

High

687088

RS10A
Small ribosomal subunit protein eS10A

1

4

High-throughput

0.437

High

645097

EPT1
Choline/ethanolaminephosphotransferase 1

1

1

High-throughput

0.417

High

687069

ERV29
ER-derived vesicles protein ERV29

2

0

High-throughput

0.319

High

528555

CP51
Lanosterol 14-alpha demethylase CYP51

1

0

High-throughput

0.282

High

636278

ACO1
Acyl-CoA desaturase 1

1

0

High-throughput

0.282

High

678029

HSP30
30 kDa heat shock protein

1

0

High-throughput

0.282

High

687043

SFK1
Protein SFK1

1

0

High-throughput

0.282

High

687051

MCFS2
Medium-chain fatty acid ethyl ester synthase/esterase 2

1

0

High-throughput

0.282

High

687070

MEP3
Ammonium transporter MEP3

1

0

High-throughput

0.282

High

687071

TMEDA
Endoplasmic reticulum vesicle protein 25

1

0

High-throughput

0.282

High

687076

SHR3
Secretory component protein SHR3

1

0

High-throughput

0.282

High

687077

PDR12
ATP-dependent permease PDR12

1

0

High-throughput

0.282

High

687078

OSTD
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1

1

0

High-throughput

0.282

High

687081

EFR3
Protein EFR3

1

0

High-throughput

0.282

High

687089

FLC1
Flavin carrier protein 1

1

0

High-throughput

0.282

High

687091

TPO4
Polyamine transporter 4

1

0

High-throughput

0.282

High

687098

NAH1

1

0

High-throughput

0.282

High

554462

TRK1
High-affinity potassium transport protein

1

0

Small-scale

0.249

Low

687034

EF1B
Elongation factor 1-beta

1

0

Small-scale

0.249

Low

687079

YDC1
Alkaline ceramidase YDC1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025