HitPredict

Interactor 1: PTBP1 (P26599)
Polypyrimidine tract-binding protein 1 (PTB) (57 kDa RNA-binding protein PPTB-1) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I)
Gene: PTBP1

Interactor 2: RPTOR (Q8N122)
Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein)
Gene: RPTOR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25940091
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 557 Hs			1 1335
+	Hs
		550357 PABP1_HUMAN (3-375): 2.22e-45: 171: 13.58		RPTOR_HUMAN (1-1335): 0: 1443: 100.00
+	Hs
		1102020 PABP4_HUMAN (3-378): 2.7e-44: 168: 10.62		RPTOR_HUMAN (1-1335): 0: 1443: 100.00
+	Hs
		687475 PTBP1_HUMAN (1-557): 1.59e-121: 370: 100.00		FBXW7_HUMAN (961-1324): 9.8e-69: 248: 14.91
+	Hs
		687369 PTBP1_HUMAN (1-557): 1.59e-121: 370: 100.00		WDR5_HUMAN (1099-1334): 2.45e-64: 223: 16.88
+	Hs
		687478 PTBP1_HUMAN (1-557): 1.59e-121: 370: 100.00		SNR40_HUMAN (1246-1335): 6.42e-16: 82.9: 17.58
+	Hs
		687340 PTBP1_HUMAN (1-557): 1.59e-121: 370: 100.00		COPB2_HUMAN (1197-1333): 5.93e-15: 82.2: 15.83
+	Hs
		344115 PTBP3_HUMAN (1-557): 5.42e-102: 320: 74.01		COPB2_HUMAN (1197-1333): 5.93e-15: 82.2: 15.83
+	Hs
		550204 PABP1_HUMAN (3-375): 2.22e-45: 171: 13.58		WDR5_HUMAN (1099-1334): 2.45e-64: 223: 16.88
+	Hs
		964916 PABP4_HUMAN (3-378): 2.7e-44: 168: 10.62		WDR5_HUMAN (1099-1334): 2.45e-64: 223: 16.88
+	Hs
		1387626 PTBP2_HUMAN (1-557): 1.86e-93: 297: 67.86		SNR40_HUMAN (1246-1335): 6.42e-16: 82.9: 17.58
+	Hs
		576488 HNRPL_HUMAN (15-252): 6.55e-10: 63.7: 13.31		FBXW7_HUMAN (961-1324): 9.8e-69: 248: 14.91
+	Hs
		576337 HNRPL_HUMAN (15-252): 6.55e-10: 63.7: 13.31		WDR5_HUMAN (1099-1334): 2.45e-64: 223: 16.88
+	Hs
		1047994 RBM20_HUMAN (59-156): 1.24e-13: 76.3: 47.00		TLE3_HUMAN (1165-1335): 3.53e-23: 108: 13.07
+	Hs
		478152 SNRPA_HUMAN (361-471): 6.98e-19: 89.1: 16.38		SNR40_HUMAN (1246-1335): 6.42e-16: 82.9: 17.58
+	Hs
		1212644 RBM20_HUMAN (59-156): 1.24e-13: 76.3: 47.00		SNR40_HUMAN (1246-1335): 6.42e-16: 82.9: 17.58
+	Hs
		576495 HNRPL_HUMAN (15-252): 6.55e-10: 63.7: 13.31		SNR40_HUMAN (1246-1335): 6.42e-16: 82.9: 17.58
+	Hs
		576296 HNRPL_HUMAN (15-252): 6.55e-10: 63.7: 13.31		COPB2_HUMAN (1197-1333): 5.93e-15: 82.2: 15.83