HitPredict

Interactor 1: DBF20 (P32328)
Serine/threonine-protein kinase DBF20 (EC 2.7.11.1)
Gene: DBF20

Interactor 2: RHO5 (P53879)
GTP-binding protein RHO5
Gene: RHO5

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	30670610
Identification Methods	protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 564 Sc			1 331
+	Hs
		325682 LATS1_HUMAN (14-555): 1.49e-145: 449: 26.30		RAC1_HUMAN (1-230): 8.61e-76: 232: 43.91
+	Hs
		681775 AKT1_HUMAN (110-538): 2.94e-136: 406: 23.41		RAC1_HUMAN (1-230): 8.61e-76: 232: 43.91
+	Hs
		564425 AKT2_HUMAN (104-538): 1.79e-138: 412: 25.00		RHOQ_HUMAN (4-222): 7.24e-56: 182: 42.92
+	Hs
		148608 CTRO_HUMAN (160-499): 8.37e-51: 190: 33.43		RHOA_HUMAN (5-229): 1.44e-77: 237: 40.89
+	Hs
		900570 MRCKA_HUMAN (119-498): 1.05e-49: 187: 32.22		RHOA_HUMAN (5-229): 1.44e-77: 237: 40.89
+	Hs
		148653 CTRO_HUMAN (160-499): 8.37e-51: 190: 33.43		RAC1_HUMAN (1-230): 8.61e-76: 232: 43.91
+	Hs
		925344 MRCKA_HUMAN (119-498): 1.05e-49: 187: 32.22		RAC1_HUMAN (1-230): 8.61e-76: 232: 43.91
+	Hs
		925229 DMPK_HUMAN (145-498): 8.99e-51: 186: 32.06		RAC1_HUMAN (1-230): 8.61e-76: 232: 43.91
+	Hs
		148636 CTRO_HUMAN (160-499): 8.37e-51: 190: 33.43		RAB1A_HUMAN (4-250): 2.99e-72: 224: 18.62
+	Hs
		892423 MRCKA_HUMAN (119-498): 1.05e-49: 187: 32.22		RAC3_HUMAN (1-218): 5.72e-73: 225: 44.95
+	Hs
		951069 MRCKA_HUMAN (119-498): 1.05e-49: 187: 32.22		RHOG_HUMAN (1-229): 1.07e-72: 225: 41.92
+	Hs
		149274 CTRO_HUMAN (160-499): 8.37e-51: 190: 33.43		RAB1B_HUMAN (4-250): 7.91e-71: 220: 19.84
+	Hs
		545430 MRCKA_HUMAN (119-498): 1.05e-49: 187: 32.22		RAC2_HUMAN (1-231): 4.56e-72: 223: 43.72
+	Hs
		892702 MRCKB_HUMAN (160-498): 6.53e-48: 182: 32.57		RAC3_HUMAN (1-218): 5.72e-73: 225: 44.95
+	Hs
		894116 MRCKA_HUMAN (119-498): 1.05e-49: 187: 32.22		CDC42_HUMAN (1-229): 1.18e-70: 219: 44.11
+	Hs
		545725 MRCKB_HUMAN (160-498): 6.53e-48: 182: 32.57		RAC2_HUMAN (1-231): 4.56e-72: 223: 43.72
+	Rn
		92842 CTRO_RAT (160-499): 2.39e-49: 186: 33.72		RHOA_RAT (5-229): 2.92e-70: 218: 40.44
+	Dm
		776947 GEK_DROME (160-498): 2.78e-48: 182: 32.28		CDC42_DROME (1-230): 2.79e-71: 221: 42.61
+	Hs
		564564 MRCKA_HUMAN (119-498): 1.05e-49: 187: 32.22		RHOQ_HUMAN (4-222): 7.24e-56: 182: 42.92
+	Hs
		564758 MRCKB_HUMAN (160-498): 6.53e-48: 182: 32.57		RHOQ_HUMAN (4-222): 7.24e-56: 182: 42.92