HitPredict

Interactor 1: VA0D (P32366)
V-type proton ATPase subunit d (V-ATPase subunit d) (V-ATPase 39 kDa subunit) (V-ATPase subunit M39) (Vacuolar proton pump subunit d)
Gene: VMA6

Interactor 2: VATF (P39111)
V-type proton ATPase subunit F (V-ATPase subunit F) (V-ATPase 14 kDa subunit) (Vacuolar proton pump subunit F)
Gene: VMA7

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	1.00	0.903

The method score is based on:

Property	Details
Experiments	11805826, 16429126, 37968396, 18467557
Identification Methods	tandem affinity purification, affinity chromatography technology, protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	ATP-synt_F~vATP-synt_AC39
Common GO terms	GO:0000139 - Golgi membrane GO:0000329 - fungal-type vacuole membrane GO:0007035 - vacuolar acidification GO:0016471 - vacuolar proton-transporting V-type ATPase complex GO:0033176 - proton-transporting V-type ATPase complex and 4 others more... GO:0046961 - proton-transporting ATPase activity, rotational mechanism GO:0048388 - endosomal lumen acidification GO:0061795 - Golgi lumen acidification GO:1902600 - proton transmembrane transport
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	345
Sc

1	118

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024