Protein: TOM70
Mitochondrial import receptor subunit TOM70 (70 kDa mitochondrial outer membrane protein) (Translocase of outer membrane 70 kDa subunit)

Gene: TOM70
Organism: Saccharomyces cerevisiae S288C
Interactions: 94
UniProt ID: P07213

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005742 - mitochondrial outer membrane translocase complex
GO:0006626 - protein targeting to mitochondrion
GO:0015450 - protein-transporting ATPase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

365568

HSP82
ATP-dependent molecular chaperone HSP82

2

20

Small-scale

0.778

High

422974

TOM70
Mitochondrial import receptor subunit TOM70

2

15

Small-scale

0.778

High

422985

STI1
Heat shock protein STI1

2

16

Small-scale

0.778

High

422987

TOM40
Mitochondrial import receptor subunit TOM40

7

1

Small-scale

0.736

High

423030

TOM22
Mitochondrial import receptor subunit TOM22

5

1

Small-scale

0.712

High

422980

HSP71
Heat shock protein SSA1

5

20

Small-scale

0.702

High

422981

HSP72
Heat shock protein SSA2

3

20

Small-scale

0.633

High

423004

TOM20
Mitochondrial import receptor subunit TOM20

2

3

Small-scale

0.631

High

422983

HSC82
ATP-dependent molecular chaperone HSC82

1

20

High-throughput

0.618

High

422989

MAS5
Mitochondrial protein import protein MAS5

2

7

Small-scale

0.602

High

422988

SIS1
Protein SIS1

3

11

Small-scale

0.594

High

422994

HS104
Heat shock protein 104

3

5

Small-scale

0.585

High

423023

DJP1
DnaJ-like protein 1

2

13

Small-scale

0.585

High

422986

ADT2
ADP,ATP carrier protein 2

2

6

Small-scale

0.584

High

423002

HSP78
Heat shock protein 78, mitochondrial

2

4

High-throughput

0.584

High

423026

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

9

High-throughput

0.584

High

422999

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

2

1

Small-scale

0.571

High

373185

COX4
Cytochrome c oxidase subunit 4, mitochondrial

2

0

Small-scale

0.569

High

423050

MIM1
Mitochondrial import protein 1

2

0

Small-scale

0.559

High

412613

KAPA
cAMP-dependent protein kinase type 1

2

6

Small-scale

0.550

High

423007

MIC60
MICOS complex subunit MIC60

2

0

Small-scale

0.547

High

422995

OAC1
Mitochondrial oxaloacetate transport protein

1

7

High-throughput

0.541

High

423038

ALO
D-arabinono-1,4-lactone oxidase

1

2

High-throughput

0.541

High

423044

UGO1
Mitochondrial fusion and transport protein UGO1

1

0

Small-scale

0.537

High

422976

PT111
Protein PET111, mitochondrial

1

0

High-throughput

0.518

High

422998

HSP7F
Heat shock protein homolog SSE1

2

20

High-throughput

0.504

High

422975

ATPA
ATP synthase subunit alpha, mitochondrial

1

7

Small-scale

0.501

High

423051

PSK2
Serine/threonine-protein kinase PSK2

1

6

High-throughput

0.501

High

423010

MAL31
Maltose permease MAL31

1

1

High-throughput

0.494

High

423022

TOK1
Outward-rectifier potassium channel TOK1

1

2

High-throughput

0.494

High

423048

ANT1
Peroxisomal adenine nucleotide transporter 1

1

5

High-throughput

0.494

High

423057

EMR1
ERMES regulator 1

1

0

Small-scale

0.480

High

389811

VDAC1
Mitochondrial outer membrane protein porin 1

1

2

Small-scale

0.479

High

422979

HSP77
Import motor subunit, mitochondrial

1

20

High-throughput

0.479

High

422984

SYKC
Lysine--tRNA ligase, cytoplasmic

1

7

High-throughput

0.479

High

422991

MSP1
Outer mitochondrial transmembrane helix translocase

1

14

Small-scale

0.479

High

423006

MCR1
NADH-cytochrome b5 reductase 2

1

4

High-throughput

0.479

High

423037

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.479

High

423043

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

1

Small-scale

0.479

High

423049

LAM6
Membrane-anchored lipid-binding protein LAM6

1

1

Small-scale

0.479

High

423056

SMC6
Structural maintenance of chromosomes protein 6

1

6

High-throughput

0.479

High

423014

OM14
Mitochondrial outer membrane protein OM14

1

0

Small-scale

0.460

High

357155

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.458

High

373319

COX8
Cytochrome c oxidase subunit 8, mitochondrial

1

0

Small-scale

0.458

High

423000

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.458

High

423003

TOM6
Mitochondrial import receptor subunit TOM6

1

0

Small-scale

0.458

High

423008

QCR10
Cytochrome b-c1 complex subunit 10, mitochondrial

1

0

Small-scale

0.458

High

423013

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.458

High

423018

PSD1
Phosphatidylserine decarboxylase proenzyme 1, mitochondrial

1

0

Small-scale

0.458

High

423032

TOM7
Mitochondrial import receptor subunit TOM7

1

0

Small-scale

0.458

High

423041

TOM5
Mitochondrial import receptor subunit TOM5

1

0

Small-scale

0.458

High

423046

CIS1
Citrinin resistance protein, mitochondrial

1

0

Small-scale

0.458

High

422990

KCC1
Calcium/calmodulin-dependent protein kinase I

1

9

High-throughput

0.457

High

423028

IKS1
Probable serine/threonine-protein kinase IKS1

1

5

High-throughput

0.457

High

423045

ISR1
Serine/threonine-protein kinase ISR1

1

1

High-throughput

0.457

High

423052

HSP42
Heat shock protein 42

1

1

Small-scale

0.457

High

423055

AHA1
Hsp90 co-chaperone AHA1

1

4

Small-scale

0.457

High

341877

ATPB
ATP synthase subunit beta, mitochondrial

1

8

High-throughput

0.445

High

423005

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

1

Small-scale

0.445

High

389032

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

6

High-throughput

0.437

High

422993

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.437

High

422996

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

2

High-throughput

0.437

High

423001

SRPR
Signal recognition particle receptor subunit alpha homolog

1

3

High-throughput

0.437

High

423009

HMT1
Protein arginine N-methyltransferase 1

1

8

High-throughput

0.437

High

423011

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

423015

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

7

High-throughput

0.437

High

423016

YHI0
Putative proline--tRNA ligase YHR020W

1

5

High-throughput

0.437

High

423027

SFH5
Phosphatidylinositol transfer protein SFH5

1

1

High-throughput

0.437

High

423031

SKP1
Suppressor of kinetochore protein 1

1

1

Small-scale

0.437

High

423033

SPC98
Spindle pole body component SPC98

1

3

High-throughput

0.437

High

423034

HST2
NAD-dependent protein deacetylase HST2

1

1

High-throughput

0.437

High

423035

ATP23
Mitochondrial inner membrane protease ATP23

1

1

High-throughput

0.437

High

423042

TIM10
Mitochondrial import inner membrane translocase subunit TIM10

1

0

Small-scale

0.426

High

422977

TBA1
Tubulin alpha-1 chain

1

12

High-throughput

0.407

High

422982

SSB1
Ribosome-associated molecular chaperone SSB1

1

20

High-throughput

0.407

High

423019

TCPZ
T-complex protein 1 subunit zeta

1

10

High-throughput

0.407

High

423040

SLG1
Protein SLG1

2

0

Small-scale

0.320

High

423012

FUI1
Uridine permease

1

0

High-throughput

0.282

High

423024

SYS1
Protein SYS1

1

0

High-throughput

0.282

High

423039

HXT15
Hexose transporter HXT15

1

0

High-throughput

0.282

High

422992

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.249

Low

422997

MET4
Transcriptional activator of sulfur metabolism MET4

1

0

High-throughput

0.249

Low

423020

SS120
Protein SSP120

1

0

High-throughput

0.249

Low

423021

PFD2
Prefoldin subunit 2

1

0

Small-scale

0.249

Low

423025

EMP47
Protein EMP47

1

0

High-throughput

0.249

Low

423029

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

423036

PDR16
Phosphatidylinositol transfer protein PDR16

1

0

High-throughput

0.249

Low

423047

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

423054

EMC6
ER membrane protein complex subunit 6

1

0

High-throughput

0.249

Low

423058

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.249

Low

422978

YB39B
Uncharacterized protein YBL039W-B

1

0

High-throughput

0.238

Low

423017

YHS2
MIP18 family protein YHR122W

1

0

High-throughput

0.238

Low

423053

ATG31
Autophagy-related protein 31

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024