HitPredict

Interactor 1: SP110 (P32380)
Spindle pole body component 110 (Extragenic suppressor of CMD1-1 mutant protein 1) (Nuclear filament-related protein 1) (Spindle pole body spacer protein SPC110)
Gene: SPC110

Interactor 2: BRE1 (Q07457)
E3 ubiquitin-protein ligase BRE1 (EC 2.3.2.27) (Brefeldin A-sensitivity protein 1) (RING-type E3 ubiquitin transferase BRE1)
Gene: BRE1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21179020
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 944 Sc			1 700
+	Hs
		1268126 MY18A_HUMAN (50-754): 2.91e-27: 122: 14.14		MRCKB_HUMAN (67-632): 1.66e-38: 156: 12.56
+	Rn
		361106 MYH6_RAT (1-760): 5.21e-36: 150: 12.11		MYH6_RAT (4-521): 1.55e-17: 89.7: 10.28
+	Hs
		149126 MY18A_HUMAN (50-754): 2.91e-27: 122: 14.14		CTRO_HUMAN (137-615): 1.43e-16: 86.6: 10.00
+	Hs
		724943 MY18A_HUMAN (50-754): 2.91e-27: 122: 14.14		MYH9_HUMAN (305-666): 1.45e-16: 86.6: 7.69
+	Hs
		724810 MYH9_HUMAN (492-925): 3.43e-18: 92.8: 8.76		ROCK1_HUMAN (141-637): 1.52e-25: 115: 13.87
+	Hs
		1268060 MY18A_HUMAN (50-754): 2.91e-27: 122: 14.14		MY18A_HUMAN (76-573): 1.31e-13: 77: 10.67
+	Hs
		148461 MYH10_HUMAN (12-579): 3.59e-24: 112: 9.79		CTRO_HUMAN (137-615): 1.43e-16: 86.6: 10.00
+	Hs
		724687 MYH10_HUMAN (12-579): 3.59e-24: 112: 9.79		MYH9_HUMAN (305-666): 1.45e-16: 86.6: 7.69
+	Hs
		725095 MYH10_HUMAN (12-579): 3.59e-24: 112: 9.79		MYH10_HUMAN (245-667): 3.3e-16: 85.5: 10.88
+	Hs
		1268099 MY18A_HUMAN (50-754): 2.91e-27: 122: 14.14		MYO5C_HUMAN (86-475): 3.22e-12: 72.3: 12.75
+	Hs
		148466 MYH11_HUMAN (492-925): 1.08e-19: 97.4: 10.14		CTRO_HUMAN (137-615): 1.43e-16: 86.6: 10.00
+	Hs
		148460 MYH9_HUMAN (492-925): 3.43e-18: 92.8: 8.76		CTRO_HUMAN (137-615): 1.43e-16: 86.6: 10.00
+	Hs
		724686 MYH9_HUMAN (492-925): 3.43e-18: 92.8: 8.76		MYH9_HUMAN (305-666): 1.45e-16: 86.6: 7.69
+	Hs
		725097 MYH10_HUMAN (12-579): 3.59e-24: 112: 9.79		MYH11_HUMAN (394-666): 8.64e-10: 64.7: 13.41
+	Ce
		361121 MYO2_CAEEL (2-701): 4.2e-23: 108: 10.52		MYO1_CAEEL (199-647): 6.8e-10: 65: 14.26
+	Hs
		725035 MYH9_HUMAN (492-925): 3.43e-18: 92.8: 8.76		MYO5C_HUMAN (86-475): 3.22e-12: 72.3: 12.75
+	Mm
		93570 DESP_MOUSE (33-682): 4.07e-18: 92.4: 14.82		MYH9_MOUSE (4-290): 1.61e-09: 63.5: 10.35