HitPredict

Interactor 1: GBP1 (P32455)
Guanylate-binding protein 1 (EC 3.6.1.-) (EC 3.6.5.-) (GTP-binding protein 1) (GBP-1) (HuGBP-1) (hGBP1) (Guanine nucleotide-binding protein 1) (Interferon-induced guanylate-binding protein 1)
Gene: GBP1

Interactor 2: GBP2 (P32456)
Guanylate-binding protein 2 (EC 3.6.5.-) (GTP-binding protein 2) (GBP-2) (HuGBP-2) (Guanine nucleotide-binding protein 2) (Interferon-induced guanylate-binding protein 2)
Gene: GBP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.865

The method score is based on:

Property Details
Experiments 28514442, 33961781, 21151871
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, bimolecular fluorescence complementation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains GBP~GBP, GBP~GBP_C, GBP_C~GBP_C
Common GO terms GO:0000139 - Golgi membrane
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
and 12 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 592
Hs

1 591
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024