Protein: BMPR2
Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II)

Gene: BMPR2
Organism: Homo sapiens
Interactions: 96
UniProt ID: Q13873

Gene Ontology (top 5):
GO:0001568 - blood vessel development
GO:0001649 - osteoblast differentiation
GO:0001707 - mesoderm formation
GO:0001893 - maternal placenta development
GO:0001935 - endothelial cell proliferation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

554132

BMP2
Bone morphogenetic protein 2

7

20

Small-scale

0.960

High

1048353

ACVR1
Activin receptor type-1

4

20

Small-scale

0.898

High

554221

BMP4
Bone morphogenetic protein 4

4

20

Small-scale

0.890

High

611728

BMP7
Bone morphogenetic protein 7

3

20

Small-scale

0.848

High

845235

GDF5
Growth/differentiation factor 5

3

20

Small-scale

0.840

High

787396

TGFR1
TGF-beta receptor type-1

3

19

Small-scale

0.828

High

1029597

CD83
CD83 antigen

2

2

High-throughput

0.811

High

1118391

GDF2
Growth/differentiation factor 2

2

20

Small-scale

0.778

High

787160

BMR1A
Bone morphogenetic protein receptor type-1A

2

20

Small-scale

0.776

High

128535

BMR1B
Bone morphogenetic protein receptor type-1B

2

20

Small-scale

0.754

High

557291

SRC
Proto-oncogene tyrosine-protein kinase Src

2

11

Small-scale

0.743

High

1118386

TRIB3
Tribbles homolog 3

1

2

Small-scale

0.740

High

1118384

LRIQ1
Leucine-rich repeat- and IQ domain-containing protein 1

2

20

High-throughput

0.726

High

532079

KIT
Mast/stem cell growth factor receptor Kit

1

12

Small-scale

0.724

High

922252

LIMK1
LIM domain kinase 1

1

20

Small-scale

0.713

High

1118375

MIB1
E3 ubiquitin-protein ligase MIB1

1

5

High-throughput

0.691

High

1118365

KGP1
cGMP-dependent protein kinase 1

1

7

Small-scale

0.665

High

853678

MK08
Mitogen-activated protein kinase 8

1

10

High-throughput

0.656

High

248397

GDF9
Growth/differentiation factor 9

1

20

Small-scale

0.647

High

335550

BMP10
Bone morphogenetic protein 10

1

20

Small-scale

0.647

High

470370

INHBA
Inhibin beta A chain

1

20

Small-scale

0.647

High

483488

INHBB
Inhibin beta B chain

1

20

Small-scale

0.647

High

1118371

GDF6
Growth/differentiation factor 6

1

20

Small-scale

0.647

High

1118382

MRAP2
Melanocortin-2 receptor accessory protein 2

2

5

High-throughput

0.628

High

787296

ACV1B
Activin receptor type-1B

1

19

Small-scale

0.621

High

126587

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

373920

RASN
GTPase NRas

1

5

High-throughput

0.618

High

374589

RASH
GTPase HRas

1

5

High-throughput

0.618

High

375503

RASK
GTPase KRas

1

5

High-throughput

0.618

High

466243

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.618

High

581036

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

601280

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

643197

BMP6
Bone morphogenetic protein 6

1

20

Small-scale

0.618

High

690087

AVR2A
Activin receptor type-2A

1

20

Small-scale

0.618

High

845634

MUC18
Cell surface glycoprotein MUC18

1

3

High-throughput

0.618

High

897265

CDK7
Cyclin-dependent kinase 7

1

3

High-throughput

0.618

High

910043

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.618

High

953436

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

955150

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

962034

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

962737

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.618

High

977996

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

988352

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

1015425

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.618

High

1022710

XIAP
E3 ubiquitin-protein ligase XIAP

1

11

Small-scale

0.618

High

1118363

BMPR2
Bone morphogenetic protein receptor type-2

1

20

Small-scale

0.618

High

1118367

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.618

High

1118373

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.618

High

1118381

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.618

High

1118385

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.618

High

1118388

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.618

High

1118389

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

1118394

KCNE3
Potassium voltage-gated channel subfamily E member 3

2

6

High-throughput

0.601

High

255012

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

8

High-throughput

0.575

High

669319

ACKR3
Atypical chemokine receptor 3

1

2

High-throughput

0.575

High

1118390

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

20

Small-scale

0.561

High

1118366

FHL2
Four and a half LIM domains protein 2

1

3

Small-scale

0.552

High

776813

MYH11
Myosin-11

1

1

High-throughput

0.536

High

1118378

NRSN1
Neurensin-1

1

2

High-throughput

0.536

High

1118380

MARH1
E3 ubiquitin-protein ligase MARCHF1

1

8

High-throughput

0.536

High

1118392

ASC
Apoptosis-associated speck-like protein containing a CARD

1

0

Small-scale

0.513

High

561358

TDGF1
Protein Cripto

1

7

Small-scale

0.501

High

606111

DESM
Desmin

1

1

High-throughput

0.489

High

1118374

ARMD4
Armadillo-like helical domain-containing protein 4

1

1

High-throughput

0.489

High

1118379

RN149
E3 ubiquitin-protein ligase RNF149

1

10

High-throughput

0.489

High

1118383

RUSF1
RUS family member 1

1

3

High-throughput

0.489

High

1118393

RNF11
RING finger protein 11

1

14

High-throughput

0.489

High

786597

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

9

Small-scale

0.481

High

177682

SMAD7
Mothers against decapentaplegic homolog 7

1

20

Small-scale

0.479

High

218164

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.479

High

219863

SMAD6
Mothers against decapentaplegic homolog 6

1

20

Small-scale

0.479

High

220241

FRS3
Fibroblast growth factor receptor substrate 3

1

2

Small-scale

0.479

High

556070

CADH1
Cadherin-1

1

10

High-throughput

0.479

High

591297

CD44
CD44 antigen

1

2

Small-scale

0.479

High

608262

EGLN
Endoglin

1

12

Small-scale

0.479

High

749769

CADH5
Cadherin-5

1

9

Small-scale

0.479

High

867961

GLR
Glucagon receptor

1

2

Small-scale

0.479

High

971508

1433E
14-3-3 protein epsilon

1

5

High-throughput

0.479

High

1041054

CAV1
Caveolin-1

1

7

Small-scale

0.479

High

1113062

CUL3
Cullin-3

1

4

High-throughput

0.479

High

1118368

TSR1
Pre-rRNA-processing protein TSR1 homolog

1

0

Small-scale

0.460

High

384668

CRYAB
Alpha-crystallin B chain

1

0

Small-scale

0.458

High

982428

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

388408

B3AT
Band 3 anion transport protein

1

7

High-throughput

0.445

High

626959

FST
Follistatin

1

5

Small-scale

0.445

High

1010031

DLK1
Protein delta homolog 1

1

12

High-throughput

0.445

High

1118364

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

3

High-throughput

0.445

High

1118377

ZNT8
Proton-coupled zinc antiporter SLC30A8

1

2

High-throughput

0.445

High

1118387

S22A4
Solute carrier family 22 member 4

1

2

High-throughput

0.445

High

1118376

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

Small-scale

0.438

High

1118372

EST3
Carboxylesterase 3

1

2

Small-scale

0.437

High

188096

MOT6
Monocarboxylate transporter 6

1

0

High-throughput

0.426

High

1118369

KLH22
Kelch-like protein 22

1

1

High-throughput

0.407

High

1118370

NTCP5
Sodium/bile acid cotransporter 5

1

3

High-throughput

0.407

High

991842

DYLT1
Dynein light chain Tctex-type 1

1

0

Small-scale

0.261

Low


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Last updated: 11Aug2025