HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: SMAG2 (Q5PRF9)
Protein Smaug homolog 2 (Smaug 2) (hSmaug2) (Sterile alpha motif domain-containing protein 4B) (SAM domain-containing protein 4B)
Gene: SAMD4B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.748

Property	Details
Experiments	29395067, 33961781, 17353931, 35271311, 36931259, 15324660, 28514442, unassigned3799
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 694
+	Hs
		971607 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		SMAG2_HUMAN (1-694): 0: 1134: 100.00
+	Hs
		972136 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		SMAG1_HUMAN (1-694): 0: 1126: 60.88
+	Hs
		990310 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		SMAG2_HUMAN (1-694): 0: 1134: 100.00
+	Hs
		729904 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		SMAG2_HUMAN (1-694): 0: 1134: 100.00
+	Hs
		691543 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		SMAG1_HUMAN (1-694): 0: 1126: 60.88
+	Hs
		990875 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		SMAG1_HUMAN (1-694): 0: 1126: 60.88
+	Hs
		730356 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		SMAG1_HUMAN (1-694): 0: 1126: 60.88
+	Hs
		730643 1433S_HUMAN (1-236): 9.9e-108: 312: 71.85		SMAG2_HUMAN (1-694): 0: 1134: 100.00
+	Hs
		1049373 1433F_HUMAN (2-242): 7.19e-106: 307: 71.43		SMAG2_HUMAN (1-694): 0: 1134: 100.00
+	Hs
		966420 1433G_HUMAN (1-242): 5.51e-105: 305: 70.33		SMAG2_HUMAN (1-694): 0: 1134: 100.00
+	Hs
		730962 1433S_HUMAN (1-236): 9.9e-108: 312: 71.85		SMAG1_HUMAN (1-694): 0: 1126: 60.88
+	Hs
		1049913 1433F_HUMAN (2-242): 7.19e-106: 307: 71.43		SMAG1_HUMAN (1-694): 0: 1126: 60.88
+	Hs
		691226 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		Q8IXP7_HUMAN (328-685): 0: 572: 100.00
+	Hs
		990472 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		Q8IXP7_HUMAN (328-685): 0: 572: 100.00
+	Hs
		730039 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		Q8IXP7_HUMAN (328-685): 0: 572: 100.00
+	Hs
		108043 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		G3V2R1_HUMAN (386-694): 3.58e-161: 469: 50.14
+	Hs
		108048 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		G3V2R1_HUMAN (386-694): 3.58e-161: 469: 50.14
+	Hs
		108044 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		G3V2R1_HUMAN (386-694): 3.58e-161: 469: 50.14
+	Hs
		108050 1433F_HUMAN (2-242): 7.19e-106: 307: 71.43		G3V2R1_HUMAN (386-694): 3.58e-161: 469: 50.14
+	Hs
		108046 1433G_HUMAN (1-242): 5.51e-105: 305: 70.33		G3V2R1_HUMAN (386-694): 3.58e-161: 469: 50.14