HitPredict

Interactor 1: EIF3C (P32497)
Eukaryotic translation initiation factor 3 subunit C (eIF3c) (Eukaryotic translation initiation factor 3 93 kDa subunit) (eIF3 p93) (Nuclear transport protein NIP1) (Translation initiation factor eIF3, p93 subunit)
Gene: NIP1

Interactor 2: EIF3G (Q04067)
Eukaryotic translation initiation factor 3 subunit G (eIF3g) (Eukaryotic translation initiation factor 3 RNA-binding subunit) (eIF-3 RNA-binding subunit) (Translation initiation factor eIF3 p33 subunit) (eIF3 p33)
Gene: TIF35

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.60 0.746

The method score is based on:

Property Details
Experiments 18599441, 12411506, 21280672, 14759368, 16554755, 16429126, 37968396
Identification Methods tandem affinity purification, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001732 - formation of cytoplasmic translation initiation complex
GO:0003743 - translation initiation factor activity
GO:0005852 - eukaryotic translation initiation factor 3 complex
GO:0006413 - translational initiation
GO:0010494 - cytoplasmic stress granule
and 3 others

more...
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 812
Sc

1 274
+ Dm
+ Hs
+ Hs

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Last updated: 15 Jul 2024