Interactor 1: EI2BE (P32501)
Translation initiation factor eIF2B subunit epsilon (GCD complex subunit GCD6) (Guanine nucleotide exchange factor subunit GCD6) (eIF2B GDP-GTP exchange factor subunit epsilon)
Gene: GCD6

Interactor 2: EI2BB (P32502)
Translation initiation factor eIF2B subunit beta (GCD complex subunit GCD7) (Guanine nucleotide exchange factor subunit GCD7) (eIF2B GDP-GTP exchange factor subunit beta)
Gene: GCD7

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.983

The method score is based on:

Property Details
Experiments 8336705, 11805826, 11805837, 16429126, 24852487, 18563728, 20805354, 23263984, 10805739, 7565788, 10852917, 16554755, 37968396, 14759368
Identification Methods coimmunoprecipitation, tandem affinity purification, anti tag coimmunoprecipitation, affinity chromatography technology, pull down, biochemical, two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains IF-2B~NTP_transferase
Common GO terms GO:0002183 - cytoplasmic translational initiation
GO:0003743 - translation initiation factor activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0005851 - eukaryotic translation initiation factor 2B complex
and 2 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 712
Sc

1 381
+ Sc
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Hs
+ Sp
+ Sc
+ Hs
+ Hs
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024