Interactor 1: MK03 (P27361)
Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (Microtubule-associated protein 2 kinase) (p44-ERK1)
Gene: MAPK3
Interactor 2: PDCD1 (Q15116)
Programmed cell death protein 1 (Protein PD-1) (hPD-1) (CD antigen CD279)
Gene: PDCD1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.55 | 1.00 | 0.747 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 37208329 |
| Identification Methods | affinity chromatography technology, pull down, enzymatic study |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~V-set |
| Common GO terms | GO:0002841 - negative regulation of T cell mediated immune response to tumor cell GO:0005886 - plasma membrane GO:0006915 - apoptotic process |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
