Interactor 1: PRP19 (P32523)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase PRP19)
Gene: PRP19
Interactor 2: SYF2 (P53277)
Pre-mRNA-splicing factor SYF2 (PRP19 complex protein 31) (Synthetic lethal with CDC40 protein 2)
Gene: SYF2
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 0.55 | 0.718 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11842115, 37968396, 11884590, 11804584, 16357217, 19617314, 20956557 |
| Identification Methods | coimmunoprecipitation, affinity chromatography technology, two hybrid, biochemical, anti tag coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000398 - mRNA splicing, via spliceosome GO:0000974 - Prp19 complex GO:0005634 - nucleus GO:0005829 - cytosol GO:0071006 - U2-type catalytic step 1 spliceosome |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
