Protein: KCC1
Calcium/calmodulin-dependent protein kinase I (EC 2.7.11.17)

Gene: KCC1, CMK1
Organism: Saccharomyces cerevisiae S288C
Interactions: 215
UniProt ID: P27466

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004683 - calcium/calmodulin-dependent protein kinase activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

449080

CALM
Calmodulin

8

20

Small-scale

0.969

High

692339

AKL1
Serine/threonine-protein kinase AKL1

1

13

High-throughput

0.691

High

376178

RAS1
Ras-like protein 1

1

2

High-throughput

0.647

High

437887

KAPC
cAMP-dependent protein kinase type 3

1

9

High-throughput

0.647

High

441336

KAPB
cAMP-dependent protein kinase type 2

1

9

High-throughput

0.647

High

445318

CDC31
Cell division control protein 31

1

20

High-throughput

0.647

High

509880

RL40A
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A

1

5

High-throughput

0.647

High

642336

MCK1
Protein kinase MCK1

1

7

High-throughput

0.647

High

656378

KC11
Casein kinase I homolog 1

1

7

High-throughput

0.647

High

692322

EDE1
EH domain-containing and endocytosis protein 1

1

1

High-throughput

0.647

High

692329

PP2C1
Protein phosphatase 2C homolog 1

1

8

High-throughput

0.647

High

692415

JJJ1
J protein JJJ1

1

2

High-throughput

0.647

High

692417

CRZ1
Transcriptional regulator CRZ1

1

1

High-throughput

0.647

High

692453

ARP8
Actin-like protein ARP8

1

3

High-throughput

0.647

High

692321

SIP2
SNF1 protein kinase subunit beta-2

1

0

High-throughput

0.614

High

692361

DDI1
DNA damage-inducible protein 1

1

0

High-throughput

0.614

High

692312

GLRX4
Monothiol glutaredoxin-4

2

5

High-throughput

0.602

High

692351

TCPD
T-complex protein 1 subunit delta

2

1

High-throughput

0.602

High

692375

GPP1
Glycerol-1-phosphate phosphohydrolase 1

2

1

High-throughput

0.602

High

692325

BMH2
Protein BMH2

2

13

Small-scale

0.595

High

526069

HSP72
Heat shock protein SSA2

2

7

High-throughput

0.585

High

692295

NSR1
Nuclear localization sequence-binding protein

1

3

High-throughput

0.579

High

692331

VPS21
Vacuolar protein sorting-associated protein 21

1

2

High-throughput

0.579

High

692432

GSF2
Glucose-signaling factor 2

2

0

High-throughput

0.577

High

578957

HSC82
ATP-dependent molecular chaperone HSC82

1

17

High-throughput

0.575

High

597399

EF3A
Elongation factor 3A

1

3

High-throughput

0.575

High

692446

NEW1
[NU+] prion formation protein 1

1

3

High-throughput

0.575

High

544021

SSB1
Ribosome-associated molecular chaperone SSB1

2

7

High-throughput

0.552

High

692310

HSP7F
Heat shock protein homolog SSE1

2

12

High-throughput

0.552

High

603599

ERS1
Cystine transporter

2

1

High-throughput

0.550

High

661379

PSA3
Proteasome subunit alpha type-3

2

3

High-throughput

0.550

High

692439

CDA1
Chitin deacetylase 1

2

1

High-throughput

0.550

High

692315

YPT7
Ypt/Rab-type GTPase YPT7

1

0

High-throughput

0.541

High

692376

AZF1
Transcription factor AZF1

1

0

High-throughput

0.541

High

692401

YPT32
GTP-binding protein YPT32/YPT11

1

0

High-throughput

0.541

High

368874

SYMC
Methionine--tRNA ligase, cytoplasmic

1

3

High-throughput

0.501

High

415000

RL39
Large ribosomal subunit protein eL39

1

2

High-throughput

0.501

High

598969

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

1

High-throughput

0.501

High

632233

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

1

High-throughput

0.501

High

663308

FPS1
Glycerol uptake/efflux facilitator protein

1

11

High-throughput

0.501

High

664524

DBR1
Lariat debranching enzyme

1

1

High-throughput

0.501

High

692296

MSP1
Outer mitochondrial transmembrane helix translocase

1

5

High-throughput

0.501

High

692299

MCM5
Minichromosome maintenance protein 5

1

4

High-throughput

0.501

High

692304

TREA
Cytosolic neutral trehalase

1

1

High-throughput

0.501

High

692308

PAH1
Phosphatidic acid phosphohydrolase 1

1

2

High-throughput

0.501

High

692311

HSP79
Heat shock protein homolog SSE2

1

13

High-throughput

0.501

High

692318

PGM1
Phosphoglucomutase 1

1

1

High-throughput

0.501

High

692324

PRX1
Peroxiredoxin PRX1, mitochondrial

1

1

High-throughput

0.501

High

692327

TREB
Probable trehalase

1

1

High-throughput

0.501

High

692337

ADCS
Aminodeoxychorismate synthase

1

1

High-throughput

0.501

High

692338

GBLP
Small ribosomal subunit protein RACK1

1

2

High-throughput

0.501

High

692340

ATG8
Autophagy-related protein 8

1

1

High-throughput

0.501

High

692345

YHR2
Uncharacterized trans-sulfuration enzyme YHR112C

1

2

High-throughput

0.501

High

692352

PIK1
Phosphatidylinositol 4-kinase PIK1

1

1

High-throughput

0.501

High

692359

VFA1
VPS4-associated protein 1

1

1

High-throughput

0.501

High

692364

WRIP1
DNA-dependent ATPase MGS1

1

3

High-throughput

0.501

High

692369

6P21
6-phosphofructo-2-kinase 1

1

2

High-throughput

0.501

High

692370

SER33
D-3-phosphoglycerate dehydrogenase 2

1

2

High-throughput

0.501

High

692373

DOT5
Peroxiredoxin DOT5

1

2

High-throughput

0.501

High

692392

LSM1
LSM1-LSM7 complex subunit LSM1

1

2

High-throughput

0.501

High

692393

ALY2
Arrestin-related trafficking adapter 3

1

1

High-throughput

0.501

High

692396

EFM3
Protein-lysine N-methyltransferase EFM3

1

5

High-throughput

0.501

High

692399

RIR4
Ribonucleoside-diphosphate reductase small chain 2

1

1

High-throughput

0.501

High

692404

MSN5
Protein MSN5

1

6

High-throughput

0.501

High

692407

STR3
Cystathionine beta-lyase

1

2

High-throughput

0.501

High

692427

VPS60
Vacuolar protein-sorting-associated protein 60

1

1

High-throughput

0.501

High

692428

HAS1
ATP-dependent RNA helicase HAS1

1

1

High-throughput

0.501

High

692436

DBP9
ATP-dependent RNA helicase DBP9

1

1

High-throughput

0.501

High

692441

TPO1
Polyamine transporter 1

1

2

High-throughput

0.501

High

692426

GCN5
Histone acetyltransferase GCN5

1

1

High-throughput

0.489

High

150334

DIF1
Damage-regulated import facilitator 1

1

0

High-throughput

0.480

High

455608

TRPD
Anthranilate phosphoribosyltransferase

1

0

High-throughput

0.480

High

470633

ERG20
Farnesyl pyrophosphate synthase

1

0

High-throughput

0.480

High

585123

SYFB
Phenylalanine--tRNA ligase beta subunit

1

0

High-throughput

0.480

High

617851

DDR48
Stress protein DDR48

1

0

High-throughput

0.480

High

624454

RDS2
Regulator of drug sensitivity 2

1

0

High-throughput

0.480

High

626625

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.480

High

692301

GLNA
Glutamine synthetase

1

0

High-throughput

0.480

High

692305

PHA2
Probable prephenate dehydratase

1

0

High-throughput

0.480

High

692317

SERC
Phosphoserine aminotransferase

1

0

High-throughput

0.480

High

692320

NPL4
Nuclear protein localization protein 4

1

0

High-throughput

0.480

High

692323

YBF5
Deoxyribonuclease Tat-D

1

0

High-throughput

0.480

High

692332

NNRD
ATP-dependent

1

0

High-throughput

0.480

High

692333

PMU1
Probable phosphoglycerate mutase PMU1

1

0

High-throughput

0.480

High

692334

SPC42
Spindle pole body component SPC42

1

0

High-throughput

0.480

High

692335

DRE2
Fe-S cluster assembly protein DRE2

1

0

High-throughput

0.480

High

692336

AIM29
Altered inheritance rate of mitochondria protein 29

1

0

High-throughput

0.480

High

692342

REI1
Cytoplasmic 60S subunit biogenesis factor REI1

1

0

High-throughput

0.480

High

692344

YHJ3
Uncharacterized protein YHR033W

1

0

High-throughput

0.480

High

692348

COX23
Cytochrome c oxidase-assembly factor COX23, mitochondrial

1

0

High-throughput

0.480

High

692350

RGD3
Rho-GTPase-activating protein RGD3

1

0

High-throughput

0.480

High

692360

RTR1
RNA polymerase II subunit B1 CTD phosphatase RTR1

1

0

High-throughput

0.480

High

692366

SIP5
Protein SIP5

1

0

High-throughput

0.480

High

692368

SECU
Securin

1

0

High-throughput

0.480

High

692377

BUD6
Bud site selection protein 6

1

0

High-throughput

0.480

High

692383

IGD1
Inhibitor of glycogen debranching 1

1

0

High-throughput

0.480

High

692386

ARC1
tRNA-aminoacylation cofactor ARC1

1

0

High-throughput

0.480

High

692387

IDS2
IME2-dependent-signaling protein

1

0

High-throughput

0.480

High

692391

GLG2
Glycogenin-2

1

0

High-throughput

0.480

High

692395

GPN1
GPN-loop GTPase 1

1

0

High-throughput

0.480

High

692398

APT1
Adenine phosphoribosyltransferase 1

1

0

High-throughput

0.480

High

692402

SKP1
Suppressor of kinetochore protein 1

1

0

High-throughput

0.480

High

692409

YGD9
Putative uncharacterized oxidoreductase YGL039W

1

0

High-throughput

0.480

High

692410

PIB2
Glutamine sensor PIB2

1

0

High-throughput

0.480

High

692411

YG3A
Uncharacterized protein YGR130C

1

0

High-throughput

0.480

High

692425

UME1
Transcriptional regulatory protein UME1

1

0

High-throughput

0.480

High

692434

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.480

High

692435

NHEJ1
Non-homologous end-joining protein 1

1

0

High-throughput

0.480

High

692440

MDM36
Mitochondrial distribution and morphology protein 36

1

0

High-throughput

0.480

High

692450

APC9
Anaphase-promoting complex subunit 9

1

0

High-throughput

0.480

High

692454

STB3
Protein STB3

1

0

High-throughput

0.480

High

692458

ECM3
Protein ECM3

1

0

High-throughput

0.480

High

692298

BMH1
Protein BMH1

1

13

Small-scale

0.479

High

692346

SDO1L
Restriction of telomere capping protein 3

1

1

Small-scale

0.479

High

692413

GIS2
Zinc finger protein GIS2

1

1

High-throughput

0.479

High

451995

TOM70
Mitochondrial import receptor subunit TOM70

1

9

High-throughput

0.457

High

503901

RL27B
Large ribosomal subunit protein eL27B

1

1

High-throughput

0.457

High

534049

HSF
Heat shock transcription factor

1

2

Small-scale

0.457

High

548180

BIK1
Nuclear fusion protein BIK1

1

5

High-throughput

0.457

High

600658

SEC2
Rab guanine nucleotide exchange factor SEC2

1

1

High-throughput

0.457

High

636280

ACO1
Acyl-CoA desaturase 1

1

1

High-throughput

0.457

High

642013

DPOE
DNA polymerase epsilon catalytic subunit A

1

1

Small-scale

0.457

High

644657

MAG
DNA-3-methyladenine glycosylase

1

1

High-throughput

0.457

High

692300

RF1M
Peptide chain release factor 1, mitochondrial

1

1

High-throughput

0.457

High

692306

CDC11
Cell division control protein 11

1

1

High-throughput

0.457

High

692307

SPT16
FACT complex subunit SPT16

1

1

High-throughput

0.457

High

692309

SRP40
Suppressor protein SRP40

1

1

High-throughput

0.457

High

692347

YNG2
Chromatin modification-related protein YNG2

1

1

High-throughput

0.457

High

692349

TOM71
Protein TOM71

1

9

High-throughput

0.457

High

692354

RS26B
Small ribosomal subunit protein eS26B

1

1

High-throughput

0.457

High

692355

OXA1
Mitochondrial inner membrane protein OXA1

1

1

High-throughput

0.457

High

692365

MMF1
Protein MMF1, mitochondrial

1

1

High-throughput

0.457

High

692367

CYB5
Cytochrome b5

1

1

High-throughput

0.457

High

692372

RL34B
Large ribosomal subunit protein eL34B

1

1

High-throughput

0.457

High

692374

AIM21
Altered inheritance of mitochondria protein 21

1

1

High-throughput

0.457

High

692378

VATH
V-type proton ATPase subunit H

1

1

High-throughput

0.457

High

692381

AQY3
Aquaglycerol porin AQY3

1

11

High-throughput

0.457

High

692382

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

1

3

High-throughput

0.457

High

692388

RL17B
Large ribosomal subunit protein uL22B

1

2

High-throughput

0.457

High

692389

PIR5
Cell wall protein PIR5

1

1

High-throughput

0.457

High

692394

AVT1
Vacuolar amino acid transporter 1

1

7

High-throughput

0.457

High

692406

MGA1
Protein MGA1

1

3

High-throughput

0.457

High

692416

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

2

High-throughput

0.457

High

692418

HDA1
Histone deacetylase HDA1

1

12

High-throughput

0.457

High

692421

NUP49
Nucleoporin NUP49/NSP49

1

2

High-throughput

0.457

High

692422

FOX2
Peroxisomal hydratase-dehydrogenase-epimerase

1

1

High-throughput

0.457

High

692437

URN1
Pre-mRNA-splicing factor URN1

1

1

High-throughput

0.457

High

692447

FSF1
Sideroflexin FSF1

1

1

High-throughput

0.457

High

692449

NOP53
Ribosome biogenesis protein NOP53

1

1

High-throughput

0.457

High

692452

SSF2
Ribosome biogenesis protein SSF2

1

1

High-throughput

0.457

High

692456

PRM4
Pheromone-regulated membrane protein 4

1

1

High-throughput

0.457

High

358978

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

1

High-throughput

0.445

High

386596

TBB
Tubulin beta chain

1

2

High-throughput

0.445

High

394298

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

450538

FAS1
Fatty acid synthase subunit beta

1

2

High-throughput

0.445

High

453454

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.445

High

523230

HSP71
Heat shock protein SSA1

1

7

High-throughput

0.445

High

572531

ALF
Fructose-bisphosphate aldolase

1

1

High-throughput

0.445

High

692316

PRS7
26S proteasome regulatory subunit 7 homolog

1

7

High-throughput

0.445

High

692326

TSA1
Peroxiredoxin TSA1

1

1

High-throughput

0.445

High

692363

SSB2
Ribosome-associated molecular chaperone SSB2

1

7

High-throughput

0.445

High

692384

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

1

High-throughput

0.445

High

692403

ACS2
Acetyl-coenzyme A synthetase 2

1

1

High-throughput

0.445

High

692420

ACAC
Acetyl-CoA carboxylase

1

1

High-throughput

0.445

High

692297

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

439269

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.426

High

692380

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.426

High

692423

IMA1
Importin subunit alpha

1

0

High-throughput

0.426

High

692451

SYWC
Tryptophan--tRNA ligase, cytoplasmic

1

0

High-throughput

0.426

High

692455

RUVB2
RuvB-like protein 2

1

0

High-throughput

0.426

High

368610

PMG1
Phosphoglycerate mutase 1

1

1

High-throughput

0.407

High

613536

ADT2
ADP,ATP carrier protein 2

1

1

High-throughput

0.407

High

644725

CLH
Clathrin heavy chain

1

1

High-throughput

0.407

High

692328

SPT7
SAGA complex subunit SPT7

1

3

High-throughput

0.407

High

521083

PT122
Protein PET122, mitochondrial

2

0

High-throughput

0.314

High

692303

VPH2
Vacuolar ATPase assembly integral membrane protein VPH2

1

0

High-throughput

0.279

Low

357757

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

1

0

High-throughput

0.261

Low

473516

LEUR
Regulatory protein LEU3

1

0

High-throughput

0.261

Low

567668

ACOX
Acyl-coenzyme A oxidase

1

0

High-throughput

0.261

Low

645796

VATE
V-type proton ATPase subunit E

1

0

High-throughput

0.261

Low

692313

TMT1
Trans-aconitate 3-methyltransferase

1

0

High-throughput

0.261

Low

692314

GPT1
Glycerol-3-phosphate O-acyltransferase 1

1

0

High-throughput

0.261

Low

692319

MFT1
THO complex subunit MFT1

1

0

High-throughput

0.261

Low

692330

MNR2
Manganese resistance protein MNR2

1

0

High-throughput

0.261

Low

692341

MCFS2
Medium-chain fatty acid ethyl ester synthase/esterase 2

1

0

High-throughput

0.261

Low

692343

LEO1
RNA polymerase-associated protein LEO1

1

0

High-throughput

0.261

Low

692353

HPH2
Protein HPH2

1

0

High-throughput

0.261

Low

692356

GTT3
Glutathione transferase 3

1

0

High-throughput

0.261

Low

692357

GIP2
GLC7-interacting protein 2

1

0

High-throughput

0.261

Low

692358

IES5
Ino eighty subunit 5

1

0

High-throughput

0.261

Low

692362

COG3
Conserved oligomeric Golgi complex subunit 3

1

0

High-throughput

0.261

Low

692371

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.261

Low

692385

RPA43
DNA-directed RNA polymerase I subunit RPA43

1

0

High-throughput

0.261

Low

692390

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.261

Low

692397

GCST
Aminomethyltransferase, mitochondrial

1

0

High-throughput

0.261

Low

692400

SPT20
SAGA complex subunit SPT20

1

0

High-throughput

0.261

Low

692405

NBP1
NAP1-binding protein

1

0

High-throughput

0.261

Low

692408

KXD1
Biogenesis of lysosome-related organelles complex 1 subunit KXD1

1

0

High-throughput

0.261

Low

692412

YN93
Uncharacterized hydrolase YNR064C

1

0

High-throughput

0.261

Low

692414

CWC25
Pre-mRNA-splicing factor CWC25

1

0

High-throughput

0.261

Low

692419

ORN
Oligoribonuclease, mitochondrial

1

0

High-throughput

0.261

Low

692424

ATG21
Autophagy-related protein 21

1

0

High-throughput

0.261

Low

692429

RCF1
Respiratory supercomplex factor 1, mitochondrial

1

0

High-throughput

0.261

Low

692430

YMX7
Probable ADP-ribose 1''-phosphate phosphatase YML087W

1

0

High-throughput

0.261

Low

692431

ERB1
Ribosome biogenesis protein ERB1

1

0

High-throughput

0.261

Low

692438

BSP1
F-actin capping regulator BSP1

1

0

High-throughput

0.261

Low

692442

IRC19
Increased recombination centers protein 19

1

0

High-throughput

0.261

Low

692443

YL030
Putative uncharacterized protein YLR030W

1

0

High-throughput

0.261

Low

692444

VHS3
Phosphopantothenoylcysteine decarboxylase subunit VHS3

1

0

High-throughput

0.261

Low

692445

UTP16
U3 small nucleolar RNA-associated protein 16

1

0

High-throughput

0.261

Low

692457

RS21B
Small ribosomal subunit protein eS21B

1

0

High-throughput

0.261

Low

692302

EF2
Elongation factor 2

1

0

High-throughput

0.232

Low

692379

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.232

Low

692433

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

0

High-throughput

0.232

Low

692448

HFI1
SAGA complex subunit HFI1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025