HitPredict

Interactor 1: RPA12 (P32529)
DNA-directed RNA polymerase I subunit RPA12 (A12) (A12.2) (DNA-directed RNA polymerase I 13.7 kDa polypeptide)
Gene: RPA12

Interactor 2: RPA49 (Q01080)
DNA-directed RNA polymerase I subunit RPA49 (A49) (DNA-directed RNA polymerase I 49 kDa polypeptide)
Gene: RPA49

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.830

The method score is based on:

Property	Details
Experiments	16554755, 37968396, 24153184
Identification Methods	affinity chromatography technology, x-ray crystallography, tandem affinity purification
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	RNA_POL_M_15KD~RNA_pol_I_A49
Common GO terms	GO:0001054 - RNA polymerase I activity GO:0005634 - nucleus GO:0005736 - RNA polymerase I complex GO:0006360 - transcription by RNA polymerase I GO:0006361 - transcription initiation at RNA polymerase I promoter and 4 others more... GO:0006362 - transcription elongation by RNA polymerase I GO:0006363 - termination of RNA polymerase I transcription GO:0042254 - ribosome biogenesis GO:0042790 - nucleolar large rRNA transcription by RNA polymerase I
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	125
Sc

1	415

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024