HitPredict

Interactor 1: CDC5 (P32562)
Cell cycle serine/threonine-protein kinase CDC5/MSD2 (EC 2.7.11.21)
Gene: CDC5

Interactor 2: CDH1 (P53197)
APC/C activator protein CDH1 (CDC20 homolog 1) (Homolog of CDC twenty 1)
Gene: CDH1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.634

Property	Details
Experiments	11566880, 18500339
Identification Methods	coimmunoprecipitation, affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 566
+	Hs
		1205210 PLK2_HUMAN (76-694): 1.83e-169: 503: 32.18		CD20B_HUMAN (259-545): 1.14e-100: 315: 36.27
+	Hs
		861829 PLK1_HUMAN (88-704): 4.2e-159: 474: 29.81		CD20B_HUMAN (259-545): 1.14e-100: 315: 36.27
+	Hs
		861978 PLK1_HUMAN (88-704): 4.2e-159: 474: 29.81		FZR1_HUMAN (30-566): 8.72e-96: 302: 36.58
+	Dm
		854072 POLO_DROME (82-697): 6.45e-160: 475: 28.18		Q9W4H9_DROME (122-566): 1.17e-92: 293: 38.55
+	Hs
		1281434 PLK2_HUMAN (76-694): 1.83e-169: 503: 32.18		FBXW7_HUMAN (154-496): 7.07e-75: 253: 17.00
+	Hs
		861879 PLK1_HUMAN (88-704): 4.2e-159: 474: 29.81		FBXW7_HUMAN (154-496): 7.07e-75: 253: 17.00
+	Hs
		861722 PLK1_HUMAN (88-704): 4.2e-159: 474: 29.81		CDC20_HUMAN (13-457): 6.59e-59: 206: 16.59
+	Hs
		160853 AURKA_HUMAN (47-336): 2.08e-44: 166: 33.33		FZR1_HUMAN (30-566): 8.72e-96: 302: 36.58
+	Hs
		160697 AURKA_HUMAN (47-336): 2.08e-44: 166: 33.33		FBXW7_HUMAN (154-496): 7.07e-75: 253: 17.00
+	Hs
		160536 AURKA_HUMAN (47-336): 2.08e-44: 166: 33.33		CDC20_HUMAN (13-457): 6.59e-59: 206: 16.59
+	Dm
		332693 PLK4_DROME (80-332): 6.58e-43: 167: 34.36		Q9VDE3_DROME (320-562): 7.25e-12: 69.7: 25.61