HitPredict

Interactor 1: RPN2 (P32565)
26S proteasome regulatory subunit RPN2
Gene: RPN2

Interactor 2: PSA6 (P40302)
Proteasome subunit alpha type-6 (Macropain subunit PRE5) (Multicatalytic endopeptidase complex subunit PRE5) (Proteasome component PRE5) (Proteinase YSCE subunit PRE5)
Gene: PRE5

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	18511945, 37968396
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0034515 - proteasome storage granule GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 945 Sc			1 234
+	Hs
		637734 PSMD1_HUMAN (3-926): 0: 1116: 39.98		PSA2_HUMAN (1-234): 6.67e-103: 299: 28.81
+	Hs
		637529 PSMD1_HUMAN (3-926): 0: 1116: 39.98		PSA1_HUMAN (1-234): 2.47e-94: 278: 52.77
+	Hs
		156342 PSMD1_HUMAN (3-926): 0: 1116: 39.98		PSA7_HUMAN (6-234): 5.17e-92: 272: 31.47
+	Hs
		656297 PSMD1_HUMAN (3-926): 0: 1116: 39.98		PSA5_HUMAN (1-234): 3.29e-92: 272: 30.71
+	Hs
		638180 PSMD1_HUMAN (3-926): 0: 1116: 39.98		PSA4_HUMAN (1-234): 1.89e-91: 271: 31.95
+	Hs
		893734 PSMD1_HUMAN (3-926): 0: 1116: 39.98		PSA6_HUMAN (1-234): 2.43e-89: 265: 24.79
+	Hs
		686 A0A087WW66_HUMAN (3-926): 0: 1016: 36.69		PSA2_HUMAN (1-234): 6.67e-103: 299: 28.81
+	Hs
		685 A0A087WW66_HUMAN (3-926): 0: 1016: 36.69		PSA1_HUMAN (1-234): 2.47e-94: 278: 52.77
+	Hs
		689 A0A087WW66_HUMAN (3-926): 0: 1016: 36.69		PSA5_HUMAN (1-234): 3.29e-92: 272: 30.71
+	Hs
		688 A0A087WW66_HUMAN (3-926): 0: 1016: 36.69		PSA4_HUMAN (1-234): 1.89e-91: 271: 31.95
+	Hs
		699 A0A087WW66_HUMAN (3-926): 0: 1016: 36.69		PSA6_HUMAN (1-234): 2.43e-89: 265: 24.79
+	Dm
		522504 PSMD1_DROME (1-927): 0: 990: 36.04		PSA1_DROME (1-234): 5.39e-94: 278: 46.64
+	Dm
		1278636 PSMD1_DROME (1-927): 0: 990: 36.04		PSA5_DROME (1-234): 5.2e-93: 274: 31.28
+	Dm
		574031 PSMD1_DROME (1-927): 0: 990: 36.04		PSA4_DROME (1-234): 3.49e-89: 265: 30.71
+	Sc
		689159 RPN2_YEAST (1-945): 0: 1119: 100.00		PSA5_YEAST (3-234): 1.78e-32: 120: 34.44
+	Hs
		637679 PSMD2_HUMAN (9-770): 0: 760: 17.31		PSA2_HUMAN (1-234): 6.67e-103: 299: 28.81
+	Hs
		637407 PSMD2_HUMAN (9-770): 0: 760: 17.31		PSA1_HUMAN (1-234): 2.47e-94: 278: 52.77
+	Hs
		156281 PSMD2_HUMAN (9-770): 0: 760: 17.31		PSA7_HUMAN (6-234): 5.17e-92: 272: 31.47
+	Hs
		656214 PSMD2_HUMAN (9-770): 0: 760: 17.31		PSA5_HUMAN (1-234): 3.29e-92: 272: 30.71
+	Hs
		638122 PSMD2_HUMAN (9-770): 0: 760: 17.31		PSA4_HUMAN (1-234): 1.89e-91: 271: 31.95