HitPredict

Interactor 1: RPN2 (P32565)
26S proteasome regulatory subunit RPN2
Gene: RPN2

Interactor 2: RPN5 (Q12250)
26S proteasome regulatory subunit RPN5 (Proteasome non-ATPase subunit 5)
Gene: RPN5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.746

Property	Details
Experiments	11805837, 16554755, 16429126, 37968396, 21289098, 22307589, 22940862
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology, biochemical, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0034515 - proteasome storage granule GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 945 Sc			1 445
+	Hs
		122075 PSMD1_HUMAN (3-926): 0: 1116: 39.98		PSD12_HUMAN (7-443): 3.17e-131: 387: 40.45
+	Hs
		121840 PSMD1_HUMAN (3-926): 0: 1116: 39.98		PSD11_HUMAN (20-435): 2.54e-93: 289: 12.68
+	Hs
		678 A0A087WW66_HUMAN (3-926): 0: 1016: 36.69		PSD12_HUMAN (7-443): 3.17e-131: 387: 40.45
+	Sc
		693378 RPN2_YEAST (1-945): 0: 1119: 100.00		RPN6_YEAST (8-434): 2.76e-73: 238: 10.58
+	Dm
		1359000 PSMD1_DROME (1-927): 0: 990: 36.04		Q9V3Z4_DROME (8-442): 1.08e-114: 347: 31.21
+	Hs
		677 A0A087WW66_HUMAN (3-926): 0: 1016: 36.69		PSD11_HUMAN (20-435): 2.54e-93: 289: 12.68
+	Dm
		1180713 PSMD1_DROME (1-927): 0: 990: 36.04		PSD11_DROME (21-435): 1.22e-90: 282: 12.41
+	Hs
		121998 PSMD2_HUMAN (9-770): 0: 760: 17.31		PSD12_HUMAN (7-443): 3.17e-131: 387: 40.45
+	Hs
		121748 PSMD2_HUMAN (9-770): 0: 760: 17.31		PSD11_HUMAN (20-435): 2.54e-93: 289: 12.68
+	At
		1323448 PSD2A_ARATH (9-770): 0: 669: 17.76		PS12A_ARATH (29-445): 2.17e-126: 375: 36.36
+	Dm
		1359378 Q9VW54_DROME (13-770): 0: 651: 17.61		Q9V3Z4_DROME (8-442): 1.08e-114: 347: 31.21
+	At
		1338956 PSD2A_ARATH (9-770): 0: 669: 17.76		PSD11_ARATH (29-435): 9.77e-86: 270: 13.01
+	Dm
		1180725 Q9VW54_DROME (13-770): 0: 651: 17.61		PSD11_DROME (21-435): 1.22e-90: 282: 12.41
+	Sp
		953211 RPN1_SCHPO (9-770): 0: 621: 18.33		RPN6_SCHPO (25-432): 2.33e-86: 272: 12.95
+	Sc
		753984 RPN1_YEAST (9-573): 1.13e-134: 430: 17.33		RPN5_YEAST (1-445): 1.91e-114: 344: 100.00
+	Sc
		753987 RPN1_YEAST (9-573): 1.13e-134: 430: 17.33		RPN6_YEAST (8-434): 2.76e-73: 238: 10.58