Protein: NOS2
Nitric oxide synthase, inducible (EC 1.14.13.39) (Inducible NO synthase) (Inducible NOS) (iNOS) (Macrophage NOS) (MAC-NOS) (NOS type II) (Peptidyl-cysteine S-nitrosylase NOS2)

Gene: NOS2
Organism: Mus musculus
Interactions: 30
UniProt ID: P29477

Gene Ontology (top 5):
GO:0001666 - response to hypoxia
GO:0004517 - nitric-oxide synthase activity
GO:0005516 - calmodulin binding
GO:0005737 - cytoplasm
GO:0005777 - peroxisome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

713200

TF65
Transcription factor p65

12

3

Small-scale

0.754

High

713190

NOS2
Nitric oxide synthase, inducible

2

10

Small-scale

0.744

High

583130

IRF1
Interferon regulatory factor 1

7

1

Small-scale

0.736

High

681964

NFKB1
Nuclear factor NF-kappa-B p105 subunit

6

4

Small-scale

0.721

High

432066

JUN
Transcription factor Jun

4

3

Small-scale

0.676

High

700386

CEBPB
CCAAT/enhancer-binding protein beta

2

2

Small-scale

0.584

High

713201

RAC2
Ras-related C3 botulinum toxin substrate 2

1

10

Small-scale

0.529

High

660919

IRF8
Interferon regulatory factor 8

1

1

Small-scale

0.515

High

713192

ACTN4
Alpha-actinin-4

1

2

Small-scale

0.515

High

713195

ELAV1
ELAV-like protein 1

1

3

Small-scale

0.515

High

713208

KKCC1
Calcium/calmodulin-dependent protein kinase kinase 1

1

3

Small-scale

0.501

High

713191

STAT3
Signal transducer and activator of transcription 3

1

3

Small-scale

0.479

High

713193

RAC1
Ras-related C3 botulinum toxin substrate 1

1

10

Small-scale

0.479

High

713194

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

2

Small-scale

0.479

High

713199

TERA
Transitional endoplasmic reticulum ATPase

1

3

Small-scale

0.479

High

713202

PGH2
Prostaglandin G/H synthase 2

1

1

Small-scale

0.479

High

713203

NR4A2
Nuclear receptor subfamily 4 group A member 2

1

4

Small-scale

0.479

High

713204

HIF1A
Hypoxia-inducible factor 1-alpha

1

1

Small-scale

0.479

High

713209

SENP3
Sentrin-specific protease 3

1

1

Small-scale

0.479

High

60075

KALRN
Kalirin

1

0

Small-scale

0.458

High

74259

EP300
Histone acetyltransferase p300

1

0

Small-scale

0.458

High

713196

PO2F2
POU domain, class 2, transcription factor 2

1

0

Small-scale

0.458

High

713197

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

Small-scale

0.458

High

713198

NOTC1
Neurogenic locus notch homolog protein 1

1

0

Small-scale

0.458

High

713207

NRIP1
Nuclear receptor-interacting protein 1

1

0

Small-scale

0.458

High

591004

KPCE
Protein kinase C epsilon type

1

1

Small-scale

0.445

High

713205

COR2A
Coronin-2A

1

1

Small-scale

0.437

High

713206

RCOR2
REST corepressor 2

1

2

Small-scale

0.437

High

713210

NCOR2
Nuclear receptor corepressor 2

1

2

Small-scale

0.437

High


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Last updated: 11Aug2025