Protein: LRWD1
Leucine-rich repeat and WD repeat-containing protein 1 (Centromere protein 33) (CENP-33) (Origin recognition complex-associated protein) (ORC-associated protein) (ORCA)

Gene: LRWD1
Organism: Homo sapiens
Interactions: 112
UniProt ID: Q9UFC0

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0000781 - chromosome, telomeric region
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1305134

DNJC7
DnaJ homolog subfamily C member 7

2

0

High-throughput

0.770

High

1033447

ORC2
Origin recognition complex subunit 2

5

0

Small-scale

0.678

High

1039916

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.656

High

1313513

RN126
E3 ubiquitin-protein ligase RNF126

3

0

High-throughput

0.638

High

1332192

STN1
CST complex subunit STN1

3

0

High-throughput

0.638

High

1354663

ORC6
Origin recognition complex subunit 6

3

0

High-throughput

0.638

High

1080443

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.618

High

1296432

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

1

Small-scale

0.618

High

1334140

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

1

Small-scale

0.618

High

217284

ORC5
Origin recognition complex subunit 5

2

3

Small-scale

0.611

High

217841

ORC4
Origin recognition complex subunit 4

2

2

Small-scale

0.611

High

1033407

ORC1
Origin recognition complex subunit 1

2

2

Small-scale

0.611

High

918084

H4
Histone H4

3

0

High-throughput

0.604

High

1271557

RPGR
X-linked retinitis pigmentosa GTPase regulator

2

0

High-throughput

0.602

High

153821

ANM5
Protein arginine N-methyltransferase 5

1

0

Small-scale

0.586

High

339083

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.586

High

932429

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.586

High

1082443

DDB1
DNA damage-binding protein 1

1

0

Small-scale

0.586

High

1172128

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.586

High

1331544

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.586

High

1346962

NLE1
Notchless protein homolog 1

1

0

High-throughput

0.586

High

1354659

LRWD1
Leucine-rich repeat and WD repeat-containing protein 1

1

0

Small-scale

0.586

High

1353956

ORC3
Origin recognition complex subunit 3

2

0

Small-scale

0.585

High

1354662

T22D4
TSC22 domain family protein 4

2

0

High-throughput

0.585

High

935337

H31
Histone H3.1

2

2

High-throughput

0.584

High

1041249

CUL1
Cullin-1

2

1

Small-scale

0.584

High

945381

PRR3
Proline-rich protein 3

1

0

High-throughput

0.578

High

370634

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

843946

FXR1
RNA-binding protein FXR1

2

0

Small-scale

0.559

High

1031295

SKP2
S-phase kinase-associated protein 2

2

0

Small-scale

0.559

High

126487

FOXE1
Forkhead box protein E1

1

3

High-throughput

0.536

High

208950

FOXS1
Forkhead box protein S1

1

3

High-throughput

0.536

High

877645

FOXG1
Forkhead box protein G1

1

3

High-throughput

0.536

High

993352

FOXM1
Forkhead box protein M1

1

3

High-throughput

0.536

High

1087458

H2B2E
Histone H2B type 2-E

1

1

High-throughput

0.536

High

1287584

GCP3
Gamma-tubulin complex component 3

1

2

High-throughput

0.536

High

1301489

GCP6
Gamma-tubulin complex component 6

1

2

High-throughput

0.536

High

1304476

MPP8
M-phase phosphoprotein 8

1

1

High-throughput

0.536

High

1306876

FOXB1
Forkhead box protein B1

1

5

High-throughput

0.536

High

1311287

GCP2
Gamma-tubulin complex component 2

1

2

High-throughput

0.536

High

1318657

FOXQ1
Forkhead box protein Q1

1

3

High-throughput

0.536

High

149387

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.517

High

385664

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.517

High

243656

DNJA2
DnaJ homolog subfamily A member 2

1

0

High-throughput

0.513

High

614156

TBG1
Tubulin gamma-1 chain

1

0

High-throughput

0.513

High

726015

ADDA
Alpha-adducin

1

0

High-throughput

0.513

High

1056469

IRF3
Interferon regulatory factor 3

1

0

High-throughput

0.513

High

1075266

TEAD2
Transcriptional enhancer factor TEF-4

1

0

High-throughput

0.513

High

1159886

MZT2A
Mitotic-spindle organizing protein 2A

1

0

High-throughput

0.513

High

1295498

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.513

High

1303824

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.513

High

1311502

FEM1A
Protein fem-1 homolog A

1

0

High-throughput

0.513

High

1348107

ALKB4
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4

1

0

High-throughput

0.513

High

245055

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.479

High

321848

WIZ
Protein Wiz

1

1

Small-scale

0.479

High

415090

CDK1
Cyclin-dependent kinase 1

1

1

Small-scale

0.479

High

524058

XRCC6
X-ray repair cross-complementing protein 6

1

1

Small-scale

0.479

High

525093

XRCC5
X-ray repair cross-complementing protein 5

1

1

Small-scale

0.479

High

625629

CDK2
Cyclin-dependent kinase 2

1

1

Small-scale

0.479

High

918753

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.479

High

952678

H33
Histone H3.3

1

2

High-throughput

0.479

High

1043277

CUL4A
Cullin-4A

1

1

Small-scale

0.479

High

1067174

BRD3
Bromodomain-containing protein 3

1

1

High-throughput

0.479

High

1160852

RFWD3
E3 ubiquitin-protein ligase RFWD3

1

1

Small-scale

0.479

High

1269844

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1306119

CDC6
Cell division control protein 6 homolog

1

2

Small-scale

0.479

High

1331895

ZN644
Zinc finger protein 644

1

1

Small-scale

0.479

High

73188

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

0

High-throughput

0.458

High

215701

AKAP8
A-kinase anchor protein 8

1

0

Small-scale

0.458

High

233671

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

267198

GEMI
Geminin

1

0

Small-scale

0.458

High

318027

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

0

High-throughput

0.458

High

323255

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

348147

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

360511

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

387670

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

391951

H2A1B
Histone H2A type 1-B/E

1

0

High-throughput

0.458

High

476515

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

Small-scale

0.458

High

553974

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

590230

CCNA2
Cyclin-A2

1

0

Small-scale

0.458

High

652516

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

721692

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

839209

EMD
Emerin

1

0

High-throughput

0.458

High

853111

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

0

Small-scale

0.458

High

964456

RUNX1
Runt-related transcription factor 1

1

0

High-throughput

0.458

High

1027311

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.458

High

1029980

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

1055500

DHX8
ATP-dependent RNA helicase DHX8

1

0

High-throughput

0.458

High

1061278

NUMA1
Nuclear mitotic apparatus protein 1

1

0

Small-scale

0.458

High

1061664

CUL7
Cullin-7

1

0

High-throughput

0.458

High

1137587

RIF1
Telomere-associated protein RIF1

1

0

Small-scale

0.458

High

1139885

OBI1
ORC ubiquitin ligase 1

1

0

Small-scale

0.458

High

1188988

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1271372

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.458

High

1281872

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

1300977

CIC
Protein capicua homolog

1

0

High-throughput

0.458

High

1313206

DDX23
Probable ATP-dependent RNA helicase DDX23

1

0

High-throughput

0.458

High

1314413

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

1354660

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1354661

NUDC
Nuclear migration protein nudC

1

0

High-throughput

0.458

High

1201933

TAXB1
Tax1-binding protein 1

1

1

High-throughput

0.437

High

1086342

H31T
Histone H3.1t

1

2

High-throughput

0.408

High

831765

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.391

High

1165357

LYPD4
Ly6/PLAUR domain-containing protein 4

2

0

High-throughput

0.328

High

324097

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.279

Low

571238

EGLN
Endoglin

1

0

High-throughput

0.279

Low

1083252

CART

1

0

High-throughput

0.279

Low

1342453

SYSM
Serine--tRNA ligase, mitochondrial

1

0

High-throughput

0.279

Low

1343188

CRAC1
Cartilage acidic protein 1

1

0

High-throughput

0.279

Low

832878

TSP3
Thrombospondin-3

1

0

High-throughput

0.249

Low

1048813

TRI29
Tripartite motif-containing protein 29

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024