HitPredict

Interactor 1: HSP7F (P32589)
Heat shock protein homolog SSE1 (Chaperone protein MSI3)
Gene: SSE1

Interactor 2: NDC80 (P40460)
Kinetochore protein NDC80 (80 kDa spindle component protein) (Nuclear division cycle protein 80) (Two-hybrid interaction with DMC1 protein 3)
Gene: NDC80

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	22908312, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 693 Sc			1 691
+	Hs
		504448 HSP7C_HUMAN (2-645): 0: 851: 27.04		DLG5_HUMAN (281-690): 1.87e-21: 102: 9.71
+	Hs
		502805 HSP7C_HUMAN (2-645): 0: 851: 27.04		LAMC1_HUMAN (251-652): 1.04e-12: 73.8: 14.09
+	Hs
		504493 HSP7C_HUMAN (2-645): 0: 851: 27.04		MY18A_HUMAN (264-674): 1.96e-12: 73: 16.20
+	Hs
		504591 HSP7C_HUMAN (2-645): 0: 851: 27.04		CFA57_HUMAN (266-645): 2.49e-11: 69.2: 12.31
+	Hs
		148327 HSP7C_HUMAN (2-645): 0: 851: 27.04		CTRO_HUMAN (301-647): 2.93e-09: 62.6: 15.16
+	Hs
		504067 HSP7C_HUMAN (2-645): 0: 851: 27.04		DCTN1_HUMAN (414-689): 2.74e-09: 62.6: 12.41
+	Hs
		148449 HS71L_HUMAN (2-646): 0: 848: 26.69		CTRO_HUMAN (301-647): 2.93e-09: 62.6: 15.16
+	Hs
		148367 HSP76_HUMAN (4-643): 0: 842: 26.28		CTRO_HUMAN (301-647): 2.93e-09: 62.6: 15.16
+	Hs
		148576 HSP72_HUMAN (2-644): 0: 840: 27.08		CTRO_HUMAN (301-647): 2.93e-09: 62.6: 15.16
+	Sc
		630954 HSP7F_YEAST (1-693): 0: 829: 100.00		USO1_YEAST (258-682): 1.9e-10: 66.5: 14.71
+	Hs
		154929 HSP74_HUMAN (6-650): 5.45e-136: 421: 38.47		NDC80_HUMAN (81-681): 2.42e-36: 147: 19.61
+	Sc
		450067 HSP73_YEAST (1-642): 5.45e-72: 247: 28.33		NDC80_YEAST (1-691): 1.63e-81: 274: 100.00
+	Sc
		494136 HSP72_YEAST (1-382): 1.15e-71: 246: 36.82		NDC80_YEAST (1-691): 1.63e-81: 274: 100.00
+	Sc
		491434 HSP71_YEAST (1-382): 7.01e-71: 244: 36.55		NDC80_YEAST (1-691): 1.63e-81: 274: 100.00
+	Hs
		320859 HS74L_HUMAN (6-650): 1.32e-134: 418: 35.85		ITSN1_HUMAN (440-691): 1.27e-09: 64: 8.68
+	Sc
		493298 HSP72_YEAST (1-382): 1.15e-71: 246: 36.82		USO1_YEAST (258-682): 1.9e-10: 66.5: 14.71
+	Sc
		490455 HSP71_YEAST (1-382): 7.01e-71: 244: 36.55		USO1_YEAST (258-682): 1.9e-10: 66.5: 14.71