Interactor 1: TF2H1 (P32780)
General transcription factor IIH subunit 1 (Basic transcription factor 2 62 kDa subunit) (BTF2 p62) (General transcription factor IIH polypeptide 1) (TFIIH basal transcription factor complex p62 subunit)
Gene: GTF2H1

Interactor 2: CDK7 (P50613)
Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)
Gene: CDK7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.758

The method score is based on:

Property Details
Experiments 7533895, 9852112, 28977422, 29568061, 9130708, 8521393, 35271311, 32707033, 36736316, 8692841, 23602568, 26340423, unassigned1655
Identification Methods biochemical, pull down, affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000439 - transcription factor TFIIH core complex
GO:0005654 - nucleoplasm
GO:0005675 - transcription factor TFIIH holo complex
GO:0006281 - DNA repair
GO:0006366 - transcription by RNA polymerase II
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 548
Hs

1 346
+ At
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024