HitPredict

Interactor 1: SLA1 (P32790)
Actin cytoskeleton-regulatory complex protein SLA1
Gene: SLA1

Interactor 2: VRP1 (P37370)
Verprolin
Gene: VRP1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	11805826, 37968396, 18467557, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology, dihydrofolate reductase reconstruction
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005935 - cellular bud neck GO:0006897 - endocytosis GO:0030479 - actin cortical patch GO:0043332 - mating projection tip
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1244 Sc			1 817
+	Hs
		554259 MUC1_HUMAN (338-1237): 8.59e-42: 169: 8.24		MUC1_HUMAN (52-810): 3.67e-45: 177: 11.30
+	Hs
		1164748 ANR11_HUMAN (442-1239): 1.89e-41: 169: 12.19		ANR11_HUMAN (29-759): 3.25e-27: 121: 14.10
+	Ce
		712432 Q95PW9_CAEEL (8-155): 1.65e-46: 174: 21.88		SC161_CAEEL (280-477): 1.88e-09: 63.5: 24.29
+	Sc
		692218 PAN1_YEAST (713-1210): 5.38e-11: 69.7: 16.79		VRP1_YEAST (1-817): 1.29e-36: 150: 100.00
+	Hs
		1017348 BPTF_HUMAN (618-1237): 6.36e-15: 82.5: 9.88		SP130_HUMAN (72-806): 3.58e-26: 117: 14.64
+	Dm
		113976 M9PB30_DROME (125-851): 1.04e-16: 88.8: 7.50		M9PB30_DROME (230-814): 3.22e-21: 102: 13.00
+	Hs
		1056953 ATX2_HUMAN (520-1240): 1.1e-09: 65.3: 8.02		MDC1_HUMAN (23-817): 1.05e-25: 116: 10.81
+	Mm
		1351630 PCLO_MOUSE (151-1049): 1.74e-16: 88: 8.79		PCLO_MOUSE (1-808): 2.05e-16: 86.6: 11.93
+	Hs
		1300971 CHD7_HUMAN (608-1142): 2.7e-20: 100: 8.50		CIC_HUMAN (10-707): 1.45e-10: 67.4: 13.59
+	Mm
		99853 F6M2J9_MOUSE (373-1096): 1.55e-16: 87.6: 7.46		F8WI37_MOUSE (1-571): 4.17e-11: 69.2: 14.19
+	Hs
		152667 KMT2C_HUMAN (196-1026): 1.34e-13: 78.4: 7.10		KMT2D_HUMAN (4-757): 1.05e-10: 68.2: 10.40
+	Mm
		1207212 NCOA6_MOUSE (138-1240): 9.17e-12: 72.2: 6.90		KMT2C_MOUSE (1-571): 4.17e-11: 69.2: 14.19
+	Hs
		152645 NCOA6_HUMAN (128-1210): 2.42e-11: 70.7: 7.02		KMT2D_HUMAN (4-757): 1.05e-10: 68.2: 10.40
+	Hs
		1057773 NCOA6_HUMAN (128-1210): 2.42e-11: 70.7: 7.02		KMT2C_HUMAN (24-667): 1.95e-10: 66.9: 12.98
+	Hs
		1231047 ATX2_HUMAN (520-1240): 1.1e-09: 65.3: 8.02		CRBG2_HUMAN (4-681): 1.19e-10: 67.7: 10.59
+	Hs
		867119 SC24C_HUMAN (619-982): 3.04e-09: 63.6: 11.41		CIC_HUMAN (10-707): 1.45e-10: 67.4: 13.59