HitPredict

Interactor 1: SLA1 (P32790)
Actin cytoskeleton-regulatory complex protein SLA1
Gene: SLA1

Interactor 2: RV167 (P39743)
Reduced viability upon starvation protein 167
Gene: RVS167

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.862

Property	Details
Experiments	11489916, 19841731, 14761940
Identification Methods	two hybrid, pull down, two hybrid pooling approach
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	SH3_1~SH3_1
Common GO terms	GO:0003779 - actin binding GO:0005737 - cytoplasm GO:0006897 - endocytosis GO:0030479 - actin cortical patch GO:0043332 - mating projection tip
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1244 Sc			1 482
+	Sc
		698000 SLA1_YEAST (1-1244): 7.36e-166: 528: 100.00		MYO5_YEAST (6-479): 1.82e-43: 166: 11.27
+	Sc
		697903 SLA1_YEAST (1-1244): 7.36e-166: 528: 100.00		MYO3_YEAST (6-482): 7.31e-39: 153: 9.82
+	Sc
		697958 SLA1_YEAST (1-1244): 7.36e-166: 528: 100.00		LSB3_YEAST (310-479): 5.12e-28: 118: 25.42
+	Sc
		697889 SLA1_YEAST (1-1244): 7.36e-166: 528: 100.00		YSC84_YEAST (384-480): 7.27e-28: 117: 30.93
+	Sp
		194039 YFHH_SCHPO (203-1209): 2.96e-21: 103: 7.48		MYO1_SCHPO (6-481): 6.69e-44: 167: 12.93
+	Hs
		1305679 ATX2_HUMAN (520-1240): 1.1e-09: 65.3: 8.02		Q9BTH3_HUMAN (3-481): 3.07e-58: 200: 15.39
+	Hs
		1052269 ATX2L_HUMAN (545-1243): 2.66e-14: 80.3: 9.59		SRC8_HUMAN (15-481): 1.07e-49: 180: 15.01
+	Ce
		70017 G5EBN5_CAEEL (879-1243): 1.28e-11: 71.7: 12.60		SH3GH_CAEEL (75-479): 1.98e-46: 167: 18.43
+	Sc
		692248 PAN1_YEAST (713-1210): 5.38e-11: 69.7: 16.79		MYO5_YEAST (6-479): 1.82e-43: 166: 11.27
+	Hs
		203224 SYNJ1_HUMAN (623-1035): 3.19e-09: 63.8: 7.86		MYO1E_HUMAN (5-480): 8.88e-45: 170: 14.14
+	Sc
		692216 PAN1_YEAST (713-1210): 5.38e-11: 69.7: 16.79		MYO3_YEAST (6-482): 7.31e-39: 153: 9.82
+	Mm
		88459 D3Z656_MOUSE (467-973): 5.94e-11: 69.5: 6.43		SH3G2_MOUSE (84-480): 8.19e-39: 146: 14.75
+	Mm
		250689 ATX2_MOUSE (155-1241): 1.33e-10: 68.4: 8.76		SH3G2_MOUSE (84-480): 8.19e-39: 146: 14.75
+	Hs
		1305672 ATX2_HUMAN (520-1240): 1.1e-09: 65.3: 8.02		SH3G2_HUMAN (84-480): 7.48e-39: 146: 14.25
+	Hs
		203248 SYNJ1_HUMAN (623-1035): 3.19e-09: 63.8: 7.86		SH3G1_HUMAN (85-480): 2.12e-38: 145: 12.78
+	Hs
		203246 SYNJ1_HUMAN (623-1035): 3.19e-09: 63.8: 7.86		SH3Y1_HUMAN (373-480): 7.66e-27: 112: 31.30
+	Hs
		203228 SYNJ1_HUMAN (623-1035): 3.19e-09: 63.8: 7.86		ITSN1_HUMAN (192-482): 9.15e-19: 91.8: 16.67
+	Dm
		993211 Q9VUH6_DROME (866-1244): 2.09e-10: 67.5: 11.69		GRAP_DROME (426-478): 3.35e-13: 70.7: 39.62
+	Hs
		827753 Q86V38_HUMAN (649-1244): 2.59e-09: 64.1: 7.89		AMPH_HUMAN (319-481): 1.86e-10: 65.2: 15.34
+	Hs
		203213 SYNJ1_HUMAN (623-1035): 3.19e-09: 63.8: 7.86		AMPH_HUMAN (319-481): 1.86e-10: 65.2: 15.34