HitPredict

Interactor 1: TIM23 (P32897)
Mitochondrial import inner membrane translocase subunit TIM23 (Membrane import machinery protein MIM23) (Mitochondrial protein import protein 3) (Mitochondrial protein import protein MAS6)
Gene: TIM23

Interactor 2: TOM22 (P49334)
Mitochondrial import receptor subunit TOM22 (Mitochondrial 17 kDa assembly protein) (Mitochondrial 22 kDa outer membrane protein) (Protein MAS17) (Translocase of outer membrane 22 kDa subunit)
Gene: TOM22

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.750

Property	Details
Experiments	25263020, 14532110, 10428870, 25124039, 19884344, 25008211, 31118508, 30463002, 21215441
Identification Methods	nuclear magnetic resonance, affinity chromatography technology, biochemical, pull down
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0030150 - protein import into mitochondrial matrix
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 222 Sc			1 152
+	Sc
		761882 TIM17_YEAST (102-211): 4.44e-33: 118: 23.64		TOM22_YEAST (1-152): 7.81e-54: 168: 100.00
+	Sc
		826223 TIM22_YEAST (107-198): 2.66e-21: 89.5: 26.09		TOM22_YEAST (1-152): 7.81e-54: 168: 100.00