HitPredict

Interactor 1: SMC1 (P32908)
Structural maintenance of chromosomes protein 1 (DA-box protein SMC1)
Gene: SMC1

Interactor 2: SCC1 (Q12158)
Sister chromatid cohesion protein 1
Gene: MCD1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.991

The method score is based on:

Property Details
Experiments 9335334, 9990856, 11805826, 11805837, 14614819, 15383284, 14614818, 31201089, 31807710, 34259632, 21441928, 11983169, 11309624, 12654244, 14613943, 16554755, 28383696, 17660750, 30109982, 29932904 and 6 others

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Identification Methods biochemical, coimmunoprecipitation, tandem affinity purification, anti tag coimmunoprecipitation, affinity chromatography technology, pull down, x-ray crystallography, fluorescent resonance energy transfer
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Rad21_Rec8~SMC_N, Rad21_Rec8_N~SMC_N
Common GO terms GO:0005634 - nucleus
GO:0006302 - double-strand break repair
GO:0007064 - mitotic sister chromatid cohesion
GO:0008278 - cohesin complex
GO:0030892 - mitotic cohesin complex
and 2 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1225
Sc

1 566
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Last updated: 15 Jul 2024