Protein: UFSP2
Ufm1-specific protease 2 (UfSP2) (EC 3.4.22.-)

Gene: UFSP2
Organism: Homo sapiens
Interactions: 122
UniProt ID: Q9NUQ7

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
GO:0006508 - proteolysis
GO:0032649 - regulation of type II interferon production

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

243075

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.716

High

521027

HLAC
HLA class I histocompatibility antigen, C alpha chain

3

1

High-throughput

0.667

High

675177

TNR6
Tumor necrosis factor receptor superfamily member 6

3

1

High-throughput

0.609

High

1390891

ASIC4
Acid-sensing ion channel 4

3

1

High-throughput

0.604

High

1393744

DDRGK
DDRGK domain-containing protein 1

2

1

High-throughput

0.601

High

682109

RBTN1
Rhombotin-1

2

0

High-throughput

0.580

High

834146

ABEC1
C->U-editing enzyme APOBEC-1

2

0

High-throughput

0.580

High

1168756

DOXA2
Dual oxidase maturation factor 2

2

0

High-throughput

0.576

High

1216409

FAXC
Failed axon connections homolog

2

0

High-throughput

0.576

High

850888

KI3L2
Killer cell immunoglobulin-like receptor 3DL2

2

3

High-throughput

0.574

High

1006037

ASIC1
Acid-sensing ion channel 1

2

1

High-throughput

0.574

High

1232139

VASN
Vasorin

2

1

High-throughput

0.574

High

1292577

AMGO3
Amphoterin-induced protein 3

2

3

High-throughput

0.574

High

1335748

MOT11
Monocarboxylate transporter 11

2

2

High-throughput

0.574

High

1399918

SIG12
Sialic acid-binding Ig-like lectin 12

2

2

High-throughput

0.574

High

1438016

CDHR5
Cadherin-related family member 5

2

5

High-throughput

0.574

High

1450058

PCDA4
Protocadherin alpha-4

2

4

High-throughput

0.574

High

1101312

SLAF1
Signaling lymphocytic activation molecule

2

4

High-throughput

0.558

High

1420328

CD244
Natural killer cell receptor 2B4

2

4

High-throughput

0.558

High

1293917

VSIG1
V-set and immunoglobulin domain-containing protein 1

2

2

High-throughput

0.549

High

1446710

TMM9B
Transmembrane protein 9B

2

1

High-throughput

0.549

High

749815

CADH5
Cadherin-5

1

2

High-throughput

0.536

High

892729

DNLI4
DNA ligase 4

1

0

High-throughput

0.529

High

250863

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

0

High-throughput

0.513

High

940468

TCL1A
T-cell leukemia/lymphoma protein 1A

1

0

High-throughput

0.513

High

951461

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.513

High

1010112

DLK1
Protein delta homolog 1

1

0

High-throughput

0.513

High

1027203

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.513

High

1136386

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.513

High

1307363

ZNG1B
Zinc-regulated GTPase metalloprotein activator 1B

1

0

High-throughput

0.513

High

1310461

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1332904

KDF1
Keratinocyte differentiation factor 1

1

0

High-throughput

0.513

High

1350150

SPP
Signal peptide peptidase

1

0

High-throughput

0.513

High

1361654

ATG4A
Cysteine protease ATG4A

1

0

High-throughput

0.513

High

1388569

SACA9
Sperm acrosome-associated protein 9

1

0

High-throughput

0.513

High

1389606

SAAL1
Protein SAAL1

1

0

High-throughput

0.513

High

1396161

LRAT2
Protein LRATD2

1

0

High-throughput

0.513

High

1404236

SEC62
Translocation protein SEC62

1

0

High-throughput

0.513

High

1410438

CYBC1
Cytochrome b-245 chaperone 1

1

0

High-throughput

0.513

High

1446160

SAYS1
SAYSvFN domain-containing protein 1

1

0

High-throughput

0.513

High

1450061

ADA18
Disintegrin and metalloproteinase domain-containing protein 18

1

0

High-throughput

0.513

High

1450057

NDRG4
Protein NDRG4

1

0

High-throughput

0.493

High

137392

BT3A3
Butyrophilin subfamily 3 member A3

1

1

High-throughput

0.489

High

188602

SIGL5
Sialic acid-binding Ig-like lectin 5

1

1

High-throughput

0.489

High

689864

CD27
CD27 antigen

1

1

High-throughput

0.489

High

700808

DMB
HLA class II histocompatibility antigen, DM beta chain

1

1

High-throughput

0.489

High

1007825

BT3A2
Butyrophilin subfamily 3 member A2

1

2

High-throughput

0.489

High

1186237

CEA21
Cell adhesion molecule CEACAM21

1

1

High-throughput

0.489

High

1292557

AMGO1
Amphoterin-induced protein 1

1

2

High-throughput

0.489

High

1433433

CSTN2
Calsyntenin-2

1

1

High-throughput

0.489

High

1450051

PDXL2
Podocalyxin-like protein 2

1

1

High-throughput

0.489

High

1450059

PCDAC
Protocadherin alpha-12

1

3

High-throughput

0.489

High

1450062

PCDB3
Protocadherin beta-3

1

3

High-throughput

0.489

High

125634

LEG9
Galectin-9

1

0

High-throughput

0.458

High

589823

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

696641

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

1255754

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1331968

ASCC1
Activating signal cointegrator 1 complex subunit 1

1

0

Small-scale

0.458

High

1334588

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.458

High

1450050

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.458

High

1450056

XPO7
Exportin-7

1

0

High-throughput

0.458

High

380165

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

1

High-throughput

0.445

High

1288337

LRRT1
Leucine-rich repeat transmembrane neuronal protein 1

1

2

High-throughput

0.445

High

1211210

ODR4
Protein odr-4 homolog

1

2

Small-scale

0.437

High

1330284

KI3L3
Killer cell immunoglobulin-like receptor 3DL3

1

2

High-throughput

0.437

High

170986

CLGN
Calmegin

1

0

High-throughput

0.426

High

538814

GTR2
Solute carrier family 2, facilitated glucose transporter member 2

1

0

High-throughput

0.426

High

552412

ADT3
ADP/ATP translocase 3

1

0

High-throughput

0.426

High

1402383

CLCC1
Chloride channel CLIC-like protein 1

1

0

High-throughput

0.426

High

47609

A0A8I5QEB2
Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3

1

3

High-throughput

0.407

High

1290414

LRRT4
Leucine-rich repeat transmembrane neuronal protein 4

1

1

High-throughput

0.407

High

1397996

MF14A
Hippocampus abundant transcript 1 protein

1

2

High-throughput

0.407

High

1450053

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

1

High-throughput

0.407

High

1450054

VGLU1
Vesicular glutamate transporter 1

1

1

High-throughput

0.407

High

1450055

VGLU2
Vesicular glutamate transporter 2

1

1

High-throughput

0.407

High

1450063

PCDGE
Protocadherin gamma-B2

1

4

High-throughput

0.407

High

1450064

PCDG5
Protocadherin gamma-A5

1

4

High-throughput

0.407

High

1322729

F177A
Protein FAM177A1

3

0

High-throughput

0.347

High

549897

CD79A
B-cell antigen receptor complex-associated protein alpha chain

3

0

High-throughput

0.345

High

1249638

PXDC2
Plexin domain-containing protein 2

3

0

High-throughput

0.345

High

1329737

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

3

0

High-throughput

0.345

High

300049

CBPD
Carboxypeptidase D

2

0

High-throughput

0.328

High

870081

KCNJ6
G protein-activated inward rectifier potassium channel 2

2

0

High-throughput

0.328

High

1407048

SNAG
Gamma-soluble NSF attachment protein

2

0

High-throughput

0.328

High

1432757

TMX1
Thioredoxin-related transmembrane protein 1

2

0

High-throughput

0.328

High

1439153

VAT1L
Synaptic vesicle membrane protein VAT-1 homolog-like

2

0

High-throughput

0.328

High

50709

HACL2
2-hydroxyacyl-CoA lyase 2

2

0

High-throughput

0.313

High

1291510

RETR3
Reticulophagy regulator 3

2

0

High-throughput

0.313

High

1292419

OSTM1
Osteopetrosis-associated transmembrane protein 1

2

0

High-throughput

0.313

High

1450052

GPC5B
G-protein coupled receptor family C group 5 member B

2

0

High-throughput

0.313

High

49821

CLRN2
Clarin-2

1

0

High-throughput

0.279

Low

231019

TYOBP
TYRO protein tyrosine kinase-binding protein

1

0

High-throughput

0.279

Low

351865

IGSF6
Immunoglobulin superfamily member 6

1

0

High-throughput

0.279

Low

642301

COMT
Catechol O-methyltransferase

1

0

High-throughput

0.279

Low

1088795

NMDE1
Glutamate receptor ionotropic, NMDA 2A

1

0

High-throughput

0.279

Low

1131943

PTCA
Protein tyrosine phosphatase receptor type C-associated protein

1

0

High-throughput

0.279

Low

1159242

SGCA
Alpha-sarcoglycan

1

0

High-throughput

0.279

Low

1193165

TIGIT
T-cell immunoreceptor with Ig and ITIM domains

1

0

High-throughput

0.279

Low

1248401

I27RA
Interleukin-27 receptor subunit alpha

1

0

High-throughput

0.279

Low

1289165

OSTB
Organic solute transporter subunit beta

1

0

High-throughput

0.279

Low

1316546

MCLN2
Mucolipin-2

1

0

High-throughput

0.279

Low

1322280

FMR1N
FMR1 neighbor protein

1

0

High-throughput

0.279

Low

1357801

CC107
Coiled-coil domain-containing protein 107

1

0

High-throughput

0.279

Low

1391151

CHMP6
Charged multivesicular body protein 6

1

0

High-throughput

0.279

Low

1392014

PLPR2
Phospholipid phosphatase-related protein type 2

1

0

High-throughput

0.279

Low

1392182

RUSF1
RUS family member 1

1

0

High-throughput

0.279

Low

1394728

LRIG1
Leucine-rich repeats and immunoglobulin-like domains protein 1

1

0

High-throughput

0.279

Low

1405054

SORT
Sortilin

1

0

High-throughput

0.279

Low

1416764

NPL
N-acetylneuraminate lyase

1

0

High-throughput

0.279

Low

1429557

RB33B
Ras-related protein Rab-33B

1

0

High-throughput

0.279

Low

1450065

SO1B1
Solute carrier organic anion transporter family member 1B1

1

0

High-throughput

0.279

Low

769308

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

844880

EAA1
Excitatory amino acid transporter 1

1

0

High-throughput

0.232

Low

1236347

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.232

Low

1244118

TMM88
Transmembrane protein 88

1

0

High-throughput

0.232

Low

1279091

RIC3
Protein RIC-3

1

0

High-throughput

0.232

Low

1314004

S35F3
Solute carrier family 35 member F3

1

0

High-throughput

0.232

Low

1391520

BSCL2
Seipin

1

0

High-throughput

0.232

Low

1393217

TM169
Transmembrane protein 169

1

0

High-throughput

0.232

Low

1402852

DIRC2
Solute carrier family 49 member 4

1

0

High-throughput

0.232

Low

1431262

DJC25
DnaJ homolog subfamily C member 25

1

0

High-throughput

0.232

Low

1450060

S22AE
Solute carrier family 22 member 14

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025