HitPredict

Interactor 1: YPT7 (P32939)
Ypt/Rab-type GTPase YPT7 (Ypt7p) (Vacuolar morphology protein 4)
Gene: YPT7

Interactor 2: GDI1 (P39958)
Rab GDP-dissociation inhibitor (Rab GDI) (Secretory pathway GDP dissociation inhibitor)
Gene: GDI1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	1.00	0.967

Property	Details
Experiments	11805837, 11116150, 10329679, 18467557, 37968396, 25948753, 11785952, 22157956
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology, protein complementation assay, two hybrid, dihydrofolate reductase reconstruction
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0016192 - vesicle-mediated transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 208 Sc			1 451
+	Hs
		678331 RAB7A_HUMAN (1-208): 8.09e-90: 263: 61.91		GDIA_HUMAN (6-450): 0: 652: 53.81
+	Hs
		838606 RAB7A_HUMAN (1-208): 8.09e-90: 263: 61.91		GDIB_HUMAN (6-450): 0: 651: 54.04
+	Hs
		678336 RAB8A_HUMAN (1-206): 1.75e-80: 240: 36.23		GDIA_HUMAN (6-450): 0: 652: 53.81
+	Hs
		838616 RAB8A_HUMAN (1-206): 1.75e-80: 240: 36.23		GDIB_HUMAN (6-450): 0: 651: 54.04
+	Mm
		838709 RAB1A_MOUSE (1-207): 3.26e-79: 237: 36.36		GDIA_MOUSE (6-450): 0: 653: 54.04
+	Hs
		678344 RAB1A_HUMAN (1-207): 3.26e-79: 237: 36.36		GDIA_HUMAN (6-450): 0: 652: 53.81
+	Hs
		678394 RAB1B_HUMAN (1-208): 3.59e-79: 237: 37.02		GDIA_HUMAN (6-450): 0: 652: 53.81
+	Hs
		838625 RAB1A_HUMAN (1-207): 3.26e-79: 237: 36.36		GDIB_HUMAN (6-450): 0: 651: 54.04
+	Hs
		838683 RAB1B_HUMAN (1-208): 3.59e-79: 237: 37.02		GDIB_HUMAN (6-450): 0: 651: 54.04
+	Dm
		284084 RAB7_DROME (1-208): 3.71e-87: 257: 58.10		Q9VLB7_DROME (6-448): 0: 625: 53.38
+	Dm
		1369986 Q9W5X0_DROME (1-208): 9.83e-84: 248: 37.02		Q9VLB7_DROME (6-448): 0: 625: 53.38
+	Sc
		699417 YPT7_YEAST (1-208): 1.11e-78: 235: 100.00		RAEP_YEAST (5-385): 5.77e-114: 348: 25.30
+	Hs
		622566 RAB7A_HUMAN (1-208): 8.09e-90: 263: 61.91		RAE1_HUMAN (4-62): 1.22e-15: 81.2: 40.68
+	Hs
		642711 RAB7A_HUMAN (1-208): 8.09e-90: 263: 61.91		RAE2_HUMAN (4-73): 2.02e-15: 80.4: 35.71
+	Hs
		622570 RAB8A_HUMAN (1-206): 1.75e-80: 240: 36.23		RAE1_HUMAN (4-62): 1.22e-15: 81.2: 40.68
+	Hs
		642718 RAB8A_HUMAN (1-206): 1.75e-80: 240: 36.23		RAE2_HUMAN (4-73): 2.02e-15: 80.4: 35.71
+	Hs
		622577 RAB1A_HUMAN (1-207): 3.26e-79: 237: 36.36		RAE1_HUMAN (4-62): 1.22e-15: 81.2: 40.68
+	Hs
		622619 RAB1B_HUMAN (1-208): 3.59e-79: 237: 37.02		RAE1_HUMAN (4-62): 1.22e-15: 81.2: 40.68
+	Hs
		642723 RAB1A_HUMAN (1-207): 3.26e-79: 237: 36.36		RAE2_HUMAN (4-73): 2.02e-15: 80.4: 35.71
+	Hs
		642743 RAB1B_HUMAN (1-208): 3.59e-79: 237: 37.02		RAE2_HUMAN (4-73): 2.02e-15: 80.4: 35.71