Interactor 1: CADH5 (P33151)
Cadherin-5 (7B4 antigen) (Vascular endothelial cadherin) (VE-cadherin) (CD antigen CD144)
Gene: CDH5

Interactor 2: VGFR2 (P35968)
Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)
Gene: KDR

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.643

The method score is based on:

Property Details
Experiments 25657827, 11950700, 18662404
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0009897 - external side of plasma membrane
GO:0030054 - cell junction
GO:0030335 - positive regulation of cell migration
GO:0030513 - positive regulation of BMP signaling pathway
and 3 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 784
Hs

1 1356
+ Mm
+ Hs
+ Xl
+ Hs
+ Xl
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024