HitPredict

Interactor 1: UBC6 (P33296)
Ubiquitin-conjugating enzyme E2 6 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 6) (Ubiquitin carrier protein UBC6) (Ubiquitin-protein ligase UBC6)
Gene: UBC6

Interactor 2: UBA4 (P38820)
Adenylyltransferase and sulfurtransferase UBA4 (Needs CLA4 to survive protein 3) (Ubiquitin-like protein activator 4) [Includes: Adenylyltransferase UBA4 (EC 2.7.7.-); Sulfurtransferase UBA4 (EC 2.8.1.-)]
Gene: UBA4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	9388185
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	ThiF~UQ_con
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 250 Sc			1 440
+	Hs
		919856 UB2D2_HUMAN (5-151): 2.74e-67: 206: 26.85		UBA5_HUMAN (4-275): 9.09e-65: 215: 20.67
+	Sc
		608684 UBC6_YEAST (1-250): 3.37e-86: 258: 100.00		UBA1_YEAST (33-418): 9.78e-41: 157: 15.29
+	Hs
		919796 UB2D2_HUMAN (5-151): 2.74e-67: 206: 26.85		UBA3_HUMAN (1-230): 6.63e-62: 209: 23.58
+	Sp
		293848 UBC4_SCHPO (5-151): 5.39e-67: 205: 28.19		UBA1_SCHPO (43-358): 2.11e-57: 205: 15.17
+	Hs
		1282360 UB2E3_HUMAN (4-151): 5.89e-62: 194: 29.33		SAE2_HUMAN (51-226): 3.88e-57: 200: 25.42
+	Sp
		193850 UBC6_SCHPO (1-191): 1.4e-58: 187: 51.74		UBA1_SCHPO (43-358): 2.11e-57: 205: 15.17
+	Hs
		607112 UB2J2_HUMAN (2-250): 6.69e-73: 224: 42.40		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Hs
		607190 UB2D4_HUMAN (5-151): 1.95e-68: 209: 27.52		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Hs
		607026 UB2D1_HUMAN (5-151): 2.16e-67: 206: 26.85		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Hs
		607050 UB2D2_HUMAN (5-151): 2.74e-67: 206: 26.85		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Hs
		607039 UB2D3_HUMAN (5-151): 7.9e-66: 202: 26.85		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Sc
		549788 UBC4_YEAST (1-151): 1.39e-65: 202: 28.76		UBA1_YEAST (33-418): 9.78e-41: 157: 15.29
+	Hs
		607129 UB2E3_HUMAN (4-151): 5.89e-62: 194: 29.33		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Hs
		607136 UB2E2_HUMAN (4-151): 3.85e-61: 192: 28.67		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Hs
		607028 UB2E1_HUMAN (4-151): 1.22e-60: 191: 28.00		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Sc
		608714 UBC13_YEAST (1-156): 2.87e-57: 181: 25.63		UBA1_YEAST (33-418): 9.78e-41: 157: 15.29
+	Hs
		607193 UB2J1_HUMAN (6-139): 7.07e-34: 125: 42.22		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Sp
		116506 UBC7_SCHPO (1-124): 8.18e-18: 79.7: 35.97		UBA1_SCHPO (43-358): 2.11e-57: 205: 15.17
+	Hs
		782203 UB2E1_HUMAN (4-151): 1.22e-60: 191: 28.00		UBA7_HUMAN (46-200): 2.1e-09: 62: 32.93
+	Sc
		608719 UBC7_YEAST (3-124): 1.08e-17: 79.3: 34.31		UBA1_YEAST (33-418): 9.78e-41: 157: 15.29