Protein: ARHG5
Rho guanine nucleotide exchange factor 5 (Ephexin-3) (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (Transforming immortalized mammary oncogene) (p60 TIM)

Gene: ARHG5, ARHGEF5
Organism: Homo sapiens
Interactions: 76
UniProt ID: Q12774

Gene Ontology (top 5):
GO:0002102 - podosome
GO:0002408 - myeloid dendritic cell chemotaxis
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005525 - GTP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

924525

GRB2
Growth factor receptor-bound protein 2

7

20

High-throughput

0.959

High

900416

RHOA
Transforming protein RhoA

4

20

Small-scale

0.873

High

666091

SHC1
SHC-transforming protein 1

3

20

High-throughput

0.848

High

338341

EGFR
Epidermal growth factor receptor

3

20

Small-scale

0.827

High

802829

CRKL
Crk-like protein

3

20

High-throughput

0.821

High

1016128

PKHG4
Puratrophin-1

2

14

High-throughput

0.783

High

802581

CRK
Adapter molecule crk

2

20

High-throughput

0.737

High

433726

LYN
Tyrosine-protein kinase Lyn

1

19

High-throughput

0.691

High

536805

TRI27
Zinc finger protein RFP

3

4

High-throughput

0.675

High

1016144

TRI54
Tripartite motif-containing protein 54

3

19

High-throughput

0.675

High

1016139

FBXW5
F-box/WD repeat-containing protein 5

1

0

High-throughput

0.656

High

1016140

HBAP1
HSPB1-associated protein 1

3

0

High-throughput

0.646

High

383768

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.618

High

665225

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.618

High

987240

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

20

High-throughput

0.618

High

1016131

WDR74
WD repeat-containing protein 74

1

13

High-throughput

0.618

High

1016155

COG6
Conserved oligomeric Golgi complex subunit 6

3

1

High-throughput

0.613

High

252997

HSF2B
Heat shock factor 2-binding protein

2

1

High-throughput

0.606

High

638276

RBTN2
Rhombotin-2

2

10

High-throughput

0.606

High

1016133

EPMIP
EPM2A-interacting protein 1

2

1

High-throughput

0.606

High

1016136

SLAI1
SLAIN motif-containing protein 1

2

1

High-throughput

0.606

High

1016150

PICK1
PRKCA-binding protein

2

1

High-throughput

0.606

High

1016151

TBC13
TBC1 domain family member 13

2

3

High-throughput

0.606

High

1016153

ZRAN1
Ubiquitin thioesterase ZRANB1

2

8

High-throughput

0.606

High

1016154

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

18

High-throughput

0.606

High

683998

1433S
14-3-3 protein sigma

2

20

High-throughput

0.601

High

169838

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

2

0

High-throughput

0.580

High

551134

ITF2
Transcription factor 4

2

0

High-throughput

0.580

High

1016142

LRAT1
Protein LRATD1

2

0

High-throughput

0.580

High

1016132

PKHG7
Pleckstrin homology domain-containing family G member 7

1

16

High-throughput

0.575

High

1016124

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

19

High-throughput

0.573

High

310614

VAPB
Vesicle-associated membrane protein-associated protein B/C

2

1

High-throughput

0.571

High

446605

SNRPA
U1 small nuclear ribonucleoprotein A

2

11

High-throughput

0.571

High

69234

MI4GD
MIF4G domain-containing protein

1

2

High-throughput

0.536

High

331383

APBA3
Amyloid-beta A4 precursor protein-binding family A member 3

1

16

High-throughput

0.536

High

358752

CRYAA
Alpha-crystallin A chain

1

3

High-throughput

0.536

High

364873

FRIL
Ferritin light chain

1

1

High-throughput

0.536

High

515846

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

4

High-throughput

0.536

High

1016127

SF3B3
Splicing factor 3B subunit 3

1

4

High-throughput

0.536

High

1016145

UBXN6
UBX domain-containing protein 6

1

1

High-throughput

0.536

High

624581

CCNE1
G1/S-specific cyclin-E1

1

0

High-throughput

0.518

High

335255

DYR
Dihydrofolate reductase

1

0

High-throughput

0.513

High

942501

CTG1B
Cancer/testis antigen 1

1

0

High-throughput

0.513

High

1016130

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

1

0

High-throughput

0.513

High

394614

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

1016146

MED28
Mediator of RNA polymerase II transcription subunit 28

1

0

Small-scale

0.493

High

1016141

LOXL4
Lysyl oxidase homolog 4

1

3

High-throughput

0.489

High

611424

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

20

High-throughput

0.481

High

1016126

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

4

High-throughput

0.481

High

319812

HERC2
E3 ubiquitin-protein ligase HERC2

1

3

High-throughput

0.479

High

359887

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

15

High-throughput

0.479

High

396925

HMGN1
Non-histone chromosomal protein HMG-14

1

4

High-throughput

0.479

High

646839

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

683299

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.479

High

848020

MECP2
Methyl-CpG-binding protein 2

1

7

High-throughput

0.479

High

904496

1433G
14-3-3 protein gamma

1

20

High-throughput

0.479

High

909489

1433E
14-3-3 protein epsilon

1

5

High-throughput

0.479

High

926975

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

952297

H33
Histone H3.3

1

6

High-throughput

0.479

High

981959

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

1016125

CUL3
Cullin-3

1

7

High-throughput

0.479

High

1016138

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1016147

CCD86
Coiled-coil domain-containing protein 86

1

5

High-throughput

0.479

High

1016135

CHSS2
Chondroitin sulfate synthase 2

1

0

High-throughput

0.460

High

1016143

SPS2
Selenide, water dikinase 2

1

0

High-throughput

0.460

High

273089

SURF6
Surfeit locus protein 6

1

0

High-throughput

0.458

High

1016152

CTNL1
Alpha-catulin

1

4

Small-scale

0.445

High

1016149

AT131
Endoplasmic reticulum transmembrane helix translocase

1

4

High-throughput

0.439

High

975645

LMNB2
Lamin-B2

1

13

High-throughput

0.437

High

1016137

BRX1
Ribosome biogenesis protein BRX1 homolog

1

2

High-throughput

0.437

High

1016129

EFHC2
EF-hand domain-containing family member C2

4

0

High-throughput

0.365

High

61516

ARG35
Rho guanine nucleotide exchange factor 35

2

0

High-throughput

0.328

High

1016134

M21D2
Nucleotidyltransferase MB21D2

2

0

High-throughput

0.316

High

224930

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.279

Low

645964

CRBB3
Beta-crystallin B3

1

0

High-throughput

0.279

Low

1016148

GLOD4
Glyoxalase domain-containing protein 4

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024