Interactor 1: PRS6B (P33298)
26S proteasome regulatory subunit 6B homolog (Protein YNT1) (Tat-binding homolog 2)
Gene: RPT3

Interactor 2: PRS8 (Q01939)
26S proteasome regulatory subunit 8 homolog (Protein CIM3) (Protein SUG1) (Tat-binding protein TBY1)
Gene: RPT6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.978

The method score is based on:

Property Details
Experiments 11742986, 11595789, 11805837, 24013205, 16554755, 36621624, 23900548, 26301997, 18467557, 37968396, 22307589
Identification Methods two hybrid, anti tag coimmunoprecipitation, affinity chromatography technology, pull down, protein complementation assay, two hybrid array, dihydrofolate reductase reconstruction, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~AAA_lid_3, AAA~Prot_ATP_ID_OB, Prot_ATP_ID_OB~Prot_ATP_ID_OB
Common GO terms GO:0000502 - proteasome complex
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0008540 - proteasome regulatory particle, base subcomplex
GO:0016887 - ATP hydrolysis activity
and 4 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 428
Sc

1 405
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ Dm
+ Dm
+ Dm
+ Rn
+ At
+ Dm
+ Dm
+ Dm
+ Hs
+ Sc
+ Sc

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Last updated: 15 Jul 2024