HitPredict

Interactor 1: PRS7 (P33299)
26S proteasome regulatory subunit 7 homolog (Protein CIM5) (Tat-binding homolog 3)
Gene: RPT1

Interactor 2: PRS4 (P40327)
26S proteasome regulatory subunit 4 homolog (Tat-binding homolog 5)
Gene: RPT2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.986

The method score is based on:

Property Details
Experiments 11742986, 22037170, 19412160, 11805826, 24013205, 16554755, 18467557, 30692646, 26301997, 16429126, 36621624, 31778111, 37968396, 15917626, 19446322
Identification Methods two hybrid, cross-linking study, pull down, tandem affinity purification, affinity chromatography technology, protein complementation assay, biochemical, anti tag coimmunoprecipitation, dihydrofolate reductase reconstruction
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~AAA_lid_3, AAA~Prot_ATP_ID_OB, AAA_lid_3~AAA_lid_3
Common GO terms GO:0000502 - proteasome complex
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006511 - ubiquitin-dependent protein catabolic process
and 6 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 467
Sc

1 437
+ Dm
+ At
+ At
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm
+ Hs
+ At
+ Dm
+ Hs
+ Rn
+ Dm
+ Hs
+ Dm
+ Sc
+ Sc
+ Dm
+ Dm

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Last updated: 15 Jul 2024