Interactor 1: PRS7 (P33299)
26S proteasome regulatory subunit 7 homolog (Protein CIM5) (Tat-binding homolog 3)
Gene: RPT1

Interactor 2: PRS10 (P53549)
26S proteasome subunit RPT4 (26S protease subunit SUG2) (Proteasomal cap subunit)
Gene: RPT4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 24013205, 19412160, 11805826, 26301997, 16429126, 18467557, 36621624, 31778111, 37968396, 15917626, 22615397
Identification Methods affinity chromatography technology, pull down, tandem affinity purification, protein complementation assay, biochemical, dihydrofolate reductase reconstruction
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~AAA_lid_3, AAA~Prot_ATP_ID_OB, AAA_lid_3~AAA_lid_3
Common GO terms GO:0000502 - proteasome complex
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0008540 - proteasome regulatory particle, base subcomplex
GO:0016887 - ATP hydrolysis activity
and 5 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 467
Sc

1 437
+ At
+ Dm
+ At
+ Hs
+ Hs
+ Rn
+ Dm
+ Dm
+ Hs
+ Hs
+ At
+ Dm
+ Sc
+ Sc
+ Dm
+ Sc
+ Dm
+ Hs
+ Dm

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Last updated: 15 Jul 2024