Interactor 1: PDR5 (P33302)
Pleiotropic ABC efflux transporter of multiple drugs (Pleiotropic drug resistance protein 5) (Suppressor of toxicity of sporidesmin)
Gene: PDR5

Interactor 2: PDR5 (P33302)
Pleiotropic ABC efflux transporter of multiple drugs (Pleiotropic drug resistance protein 5) (Suppressor of toxicity of sporidesmin)
Gene: PDR5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.925

The method score is based on:

Property Details
Experiments 11957110, 18467557, 22615397, 23831759, unassigned1933
Identification Methods two hybrid, protein complementation assay, bimolecular fluorescence complementation, ubiquitin reconstruction, dihydrofolate reductase reconstruction
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ABC2_membrane~ABC2_membrane, ABC2_membrane~ABC_tran, ABC_tran~ABC_tran
Common GO terms GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005886 - plasma membrane
GO:0008559 - ABC-type xenobiotic transporter activity
GO:0009410 - response to xenobiotic stimulus
and 6 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 1511
Sc

1 1511
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Zm
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024