HitPredict

Interactor 1: GCN1 (P33892)
eIF-2-alpha kinase activator GCN1 (General control non-derepressible protein 1) (Translational activator GCN1)
Gene: GCN1

Interactor 2: IMB2 (P38217)
Importin subunit beta-2 (Importin-104) (Karyopherin subunit beta-2) (Karyopherin-104) (Transportin) (TRN)
Gene: KAP104

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	11805826, 37968396, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 2672 Sc			1 918
+	Sc
		687918 GCN1_YEAST (1-2672): 0: 1798: 100.00		IMB3_YEAST (9-858): 2.92e-90: 311: 15.32
+	Sc
		707936 GCN1_YEAST (1-2672): 0: 1798: 100.00		IMB1_YEAST (14-865): 3.48e-86: 296: 12.25
+	Hs
		1060859 TNPO1_HUMAN (2073-2625): 4.61e-13: 77.5: 11.45		IMB1_HUMAN (13-885): 1.66e-97: 327: 11.77
+	Hs
		155576 TNPO2_HUMAN (2197-2581): 2.64e-10: 68.2: 12.16		IMB1_HUMAN (13-885): 1.66e-97: 327: 11.77
+	Hs
		1060811 CAND1_HUMAN (814-1469): 2.62e-09: 65.1: 13.54		IMB1_HUMAN (13-885): 1.66e-97: 327: 11.77
+	Hs
		268779 CAND1_HUMAN (814-1469): 2.62e-09: 65.1: 13.54		SF3B1_HUMAN (2-795): 4.69e-39: 159: 12.50
+	Sp
		251579 2AAA_SCHPO (1640-2239): 9.32e-33: 138: 12.92		IMB3_SCHPO (10-624): 2.38e-11: 70: 9.99
+	Zm
		24385 A0A1D6IHP1_MAIZE (877-1759): 3.34e-20: 100: 13.72		A0A1D6IHP1_MAIZE (12-624): 3.21e-16: 85.8: 10.69
+	Dm
		1369716 CAND1_DROME (808-2002): 4.48e-21: 104: 10.33		Q9VN44_DROME (6-641): 1.03e-14: 80.8: 11.84