Protein: LSM1
LSM1-LSM7 complex subunit LSM1 (SPB8 protein)

Gene: LSM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 134
UniProt ID: P47017

Gene Ontology (top 5):
GO:0000288 - nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000932 - P-body
GO:0003682 - chromatin binding
GO:0003729 - mRNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

678697

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

18

10

Small-scale

0.987

High

818463

LSM5
LSM complex subunit LSM5

15

16

Small-scale

0.984

High

795885

LSM2
LSM complex subunit LSM2

14

20

Small-scale

0.983

High

864124

LSM3
LSM complex subunit LSM3

15

20

Small-scale

0.983

High

864133

LSM6
LSM complex subunit LSM6

12

20

Small-scale

0.980

High

818014

LSM4
LSM complex subunit LSM4

11

20

Small-scale

0.979

High

864121

LSM7
LSM complex subunit LSM7

10

20

Small-scale

0.974

High

812070

DHH1
ATP-dependent RNA helicase DHH1

6

9

Small-scale

0.732

High

645461

XRN1
5'-3' exoribonuclease 1

6

4

Small-scale

0.729

High

864115

DCP2
m7GpppN-mRNA hydrolase

4

2

Small-scale

0.694

High

721636

RENT1
ATP-dependent helicase NAM7

4

8

Small-scale

0.692

High

780190

SN114
Pre-mRNA-splicing factor SNU114

1

16

High-throughput

0.656

High

864109

LSM8
LSM2-LSM8 complex subunit LSM8

1

17

Small-scale

0.656

High

864120

RIA1
Ribosome assembly protein 1

1

16

High-throughput

0.656

High

581879

SYKC
Lysine--tRNA ligase, cytoplasmic

2

3

High-throughput

0.621

High

864108

LSM1
LSM1-LSM7 complex subunit LSM1

1

18

Small-scale

0.621

High

394684

EF1A
Elongation factor 1-alpha

1

2

Small-scale

0.618

High

454116

DHE4
NADP-specific glutamate dehydrogenase 1

2

1

High-throughput

0.603

High

864150

DCP1
mRNA-decapping enzyme subunit 1

2

3

Small-scale

0.601

High

527039

HSP72
Heat shock protein SSA2

2

8

High-throughput

0.552

High

722051

XPO1
Exportin-1

1

4

High-throughput

0.536

High

816658

EDC3
Enhancer of mRNA-decapping protein 3

1

2

High-throughput

0.515

High

660332

STE11
Serine/threonine-protein kinase STE11

1

1

High-throughput

0.508

High

726046

FUN30
ATP-dependent helicase FUN30

1

2

High-throughput

0.508

High

740526

SIP1
SNF1 protein kinase subunit beta-1

1

1

High-throughput

0.508

High

745480

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

1

1

High-throughput

0.508

High

794275

CHK1
Serine/threonine-protein kinase CHK1

1

1

High-throughput

0.508

High

864110

MTR3
Exosome complex component MTR3

1

1

High-throughput

0.508

High

864111

BRO1
Vacuolar-sorting protein BRO1

1

1

High-throughput

0.508

High

649641

KCC2
Calcium/calmodulin-dependent protein kinase II

1

2

High-throughput

0.501

High

692392

KCC1
Calcium/calmodulin-dependent protein kinase I

1

2

High-throughput

0.501

High

763584

UTP20
U3 small nucleolar RNA-associated protein 20

1

0

High-throughput

0.493

High

483789

SWI1
SWI/SNF chromatin-remodeling complex subunit SWI1

1

0

High-throughput

0.486

High

797926

SDS24
Protein SDS24

1

0

High-throughput

0.486

High

815630

MIG3
Transcription corepressor MIG3

1

0

High-throughput

0.486

High

836683

YRB1
Ran-specific GTPase-activating protein 1

1

0

High-throughput

0.486

High

864123

SIW14
Inositol diphosphatase SIW14

1

0

High-throughput

0.486

High

864128

UFO1
Ubiquitin ligase complex F-box protein UFO1

1

0

High-throughput

0.486

High

864131

DCE
Glutamate decarboxylase

1

0

High-throughput

0.486

High

864137

CMS1
Protein CMS1

1

0

High-throughput

0.486

High

864143

INP53
Polyphosphatidylinositol phosphatase INP53

1

0

High-throughput

0.486

High

864147

PTPA2
Serine/threonine-protein phosphatase 2A activator 2

1

0

High-throughput

0.486

High

743401

TOR2
Serine/threonine-protein kinase TOR2

1

2

High-throughput

0.481

High

762843

TOR1
Serine/threonine-protein kinase TOR1

1

2

High-throughput

0.481

High

403559

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

6

Small-scale

0.479

High

436453

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

1

High-throughput

0.479

High

444559

DED1
ATP-dependent RNA helicase DED1

1

5

Small-scale

0.479

High

453966

IF4E
Eukaryotic translation initiation factor 4E

1

3

Small-scale

0.479

High

579646

HSC82
ATP-dependent molecular chaperone HSC82

1

4

High-throughput

0.479

High

584242

MS116
ATP-dependent RNA helicase MSS116, mitochondrial

1

5

High-throughput

0.479

High

707494

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

738872

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

2

High-throughput

0.479

High

752438

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.479

High

815157

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

4

Small-scale

0.479

High

815310

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

4

Small-scale

0.479

High

864113

MNP1
Large ribosomal subunit protein bL12m

1

1

High-throughput

0.479

High

864114

EIF2A
Eukaryotic translation initiation factor 2A

1

3

High-throughput

0.479

High

864125

NOP3
Serine/arginine

1

9

Small-scale

0.479

High

864134

MHR1
Large ribosomal subunit protein mL67

1

2

High-throughput

0.479

High

864136

VAM6
Vacuolar morphogenesis protein 6

1

4

High-throughput

0.479

High

864141

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.479

High

864144

MED1
Mediator of RNA polymerase II transcription subunit 1

1

2

Small-scale

0.479

High

864146

MED4
Mediator of RNA polymerase II transcription subunit 4

1

1

Small-scale

0.479

High

864149

RM23
Large ribosomal subunit protein uL13m

1

3

High-throughput

0.479

High

575354

EI2BA
Translation initiation factor eIF2B subunit alpha

1

1

High-throughput

0.464

High

672497

SYNM
Asparagine--tRNA ligase, mitochondrial

1

4

High-throughput

0.464

High

739678

SPT16
FACT complex subunit SPT16

1

2

High-throughput

0.464

High

825960

PDK1
[Pyruvate dehydrogenase

1

2

High-throughput

0.464

High

531485

RT01
Small ribosomal subunit protein mS43

1

0

High-throughput

0.458

High

623886

MYO2
Myosin-2

1

0

Small-scale

0.458

High

864129

RM34
Large ribosomal subunit protein bL34m

1

0

High-throughput

0.458

High

864138

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.458

High

864140

NMD4
Nonsense-mediated decay protein 4

1

0

Small-scale

0.458

High

524390

HSP71
Heat shock protein SSA1

1

8

High-throughput

0.445

High

545382

SSB1
Ribosome-associated molecular chaperone SSB1

1

6

High-throughput

0.445

High

739159

PRP19
Pre-mRNA-processing factor 19

1

15

Small-scale

0.445

High

741866

HSP7F
Heat shock protein homolog SSE1

1

11

High-throughput

0.445

High

554619

RM02
Large ribosomal subunit protein bL27m

1

2

High-throughput

0.437

High

569502

RM31
Large ribosomal subunit protein mL60

1

2

High-throughput

0.437

High

628163

RM33
Large ribosomal subunit protein uL30m

1

2

High-throughput

0.437

High

647922

RM08
Large ribosomal subunit protein bL17m

1

2

High-throughput

0.437

High

647992

RM20
Large ribosomal subunit protein mL58

1

2

High-throughput

0.437

High

657452

RM25
Large ribosomal subunit protein mL59

1

2

High-throughput

0.437

High

672548

RM32
Large ribosomal subunit protein bL32m

1

1

High-throughput

0.437

High

678188

IMG1
Large ribosomal subunit protein bL19m

1

2

High-throughput

0.437

High

678602

IMG2
Large ribosomal subunit protein mL49

1

2

High-throughput

0.437

High

725731

RM09
Large ribosomal subunit protein uL3m

1

3

High-throughput

0.437

High

736274

RM41
Large ribosomal subunit protein uL23m

1

2

High-throughput

0.437

High

743768

RML2
Large ribosomal subunit protein uL2m

1

2

High-throughput

0.437

High

778220

RM38
Large ribosomal subunit protein uL14m

1

2

High-throughput

0.437

High

783797

RM03
Large ribosomal subunit protein mL44

1

2

High-throughput

0.437

High

783867

RM04
Large ribosomal subunit protein uL29m

1

1

High-throughput

0.437

High

783931

RM07
Large ribosomal subunit protein uL5m

1

2

High-throughput

0.437

High

783993

RM10
Large ribosomal subunit protein uL15m

1

2

High-throughput

0.437

High

784170

RM24
Large ribosomal subunit protein bL28m

1

2

High-throughput

0.437

High

784216

RM27
Large ribosomal subunit protein mL41

1

2

High-throughput

0.437

High

784263

RM28
Large ribosomal subunit protein mL40

1

2

High-throughput

0.437

High

784327

RM17
Large ribosomal subunit protein mL46

1

2

High-throughput

0.437

High

784387

RM36
Large ribosomal subunit protein bL31m

1

1

High-throughput

0.437

High

784454

RM39
Large ribosomal subunit protein bL33m

1

2

High-throughput

0.437

High

784491

RM40
Large ribosomal subunit protein uL24m

1

2

High-throughput

0.437

High

792617

RM16
Large ribosomal subunit protein uL16m

1

2

High-throughput

0.437

High

812439

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

828545

RN49
Large ribosomal subunit protein bL21m

1

2

High-throughput

0.437

High

864112

RL4P
Large ribosomal subunit protein uL4m

1

2

High-throughput

0.437

High

864116

RM50
Large ribosomal subunit protein bL9m

1

2

High-throughput

0.437

High

864119

RM22
Large ribosomal subunit protein uL22m

1

2

High-throughput

0.437

High

864126

RM13
Large ribosomal subunit protein mL50

1

2

High-throughput

0.437

High

864130

RM01
Large ribosomal subunit protein uL1m

1

3

High-throughput

0.437

High

864135

RM35
Large ribosomal subunit protein mL38

1

2

High-throughput

0.437

High

810837

TCPG
T-complex protein 1 subunit gamma

1

1

High-throughput

0.407

High

803880

CIC1
Proteasome-interacting protein CIC1

1

0

High-throughput

0.269

Low

415110

ADT1
ADP,ATP carrier protein 1

1

0

High-throughput

0.265

Low

479988

PRTB
Cerevisin

1

0

High-throughput

0.265

Low

747195

PMP1
Plasma membrane ATPase proteolipid 1

1

0

High-throughput

0.265

Low

825928

ATC7
Phospholipid-transporting ATPase NEO1

1

0

High-throughput

0.265

Low

863373

PMT4
Dolichyl-phosphate-mannose--protein mannosyltransferase 4

1

0

High-throughput

0.265

Low

864139

GNT1
Glucose N-acetyltransferase 1

1

0

High-throughput

0.265

Low

864142

MDM32
Mitochondrial distribution and morphology protein 32

1

0

High-throughput

0.265

Low

864148

AIR2
Protein AIR2

1

0

High-throughput

0.265

Low

513089

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

736348

RM49
Large ribosomal subunit protein mL61

1

0

High-throughput

0.249

Low

747232

RM06
Large ribosomal subunit protein uL6m

1

0

High-throughput

0.249

Low

784050

RM11
Large ribosomal subunit protein uL10m

1

0

High-throughput

0.249

Low

784110

RM15
Large ribosomal subunit protein mL57

1

0

High-throughput

0.249

Low

784427

RM37
Large ribosomal subunit protein mL54

1

0

High-throughput

0.249

Low

817529

MRX1
MIOREX complex component 1

1

0

High-throughput

0.249

Low

864118

RM19
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.249

Low

864122

RN35
Large ribosomal subunit protein bL35m

1

0

High-throughput

0.249

Low

864127

ATP25
ATPase synthesis protein 25, mitochondrial

1

0

High-throughput

0.249

Low

864132

RM51
Large ribosomal subunit protein mL43

1

0

High-throughput

0.249

Low

864145

UTP23
rRNA-processing protein UTP23

1

0

High-throughput

0.249

Low

864117

YN16
Putative uncharacterized protein YNL276C

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025