HitPredict

Interactor 1: MCM4 (P33991)
DNA replication licensing factor MCM4 (EC 3.6.4.12) (CDC21 homolog) (P1-CDC21)
Gene: MCM4

Interactor 2: TONSL (Q96HA7)
Tonsoku-like protein (Inhibitor of kappa B-related protein) (I-kappa-B-related protein) (IkappaBR) (NF-kappa-B inhibitor-like protein 2) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2)
Gene: TONSL

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	21055985, 21113133
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 863 Hs			1 1378
+	Hs
		832645 MCM2_HUMAN (2-839): 0: 762: 27.95		TONSL_HUMAN (1-1378): 0: 641: 100.00
+	Hs
		708731 MCM5_HUMAN (133-846): 0: 698: 30.23		TONSL_HUMAN (1-1378): 0: 641: 100.00
+	Hs
		1055611 MCM6_HUMAN (138-842): 0: 675: 26.97		TONSL_HUMAN (1-1378): 0: 641: 100.00
+	Hs
		709010 MCM7_HUMAN (158-841): 0: 660: 29.88		TONSL_HUMAN (1-1378): 0: 641: 100.00
+	Hs
		708430 MCM4_HUMAN (1-863): 0: 952: 100.00		ANK3_HUMAN (120-617): 7.94e-49: 194: 16.63
+	Hs
		832413 MCM2_HUMAN (2-839): 0: 762: 27.95		ANK3_HUMAN (120-617): 7.94e-49: 194: 16.63
+	Hs
		1021402 MCM6_HUMAN (138-842): 0: 675: 26.97		ANK3_HUMAN (120-617): 7.94e-49: 194: 16.63
+	Hs
		527967 MCM2_HUMAN (2-839): 0: 762: 27.95		RINI_HUMAN (1008-1220): 6.76e-22: 102: 17.76
+	Hs
		1055613 MCM6_HUMAN (138-842): 0: 675: 26.97		BARD1_HUMAN (523-674): 2.95e-40: 163: 36.18