HitPredict

Interactor 1: MCM5 (P33992)
DNA replication licensing factor MCM5 (EC 3.6.4.12) (CDC46 homolog) (P1-CDC46)
Gene: MCM5

Interactor 2: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26527279, 25963833
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 734 Hs			1 136
+	Hs
		708661 MCM5_HUMAN (1-734): 0: 858: 100.00		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		708605 MCM5_HUMAN (1-734): 0: 858: 100.00		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		708690 MCM5_HUMAN (1-734): 0: 858: 100.00		H32_HUMAN (1-136): 6.5e-61: 185: 99.27
+	Hs
		708677 MCM5_HUMAN (1-734): 0: 858: 100.00		H37_HUMAN (1-136): 5.62e-59: 180: 97.06
+	Hs
		708683 MCM5_HUMAN (1-734): 0: 858: 100.00		H3C_HUMAN (1-136): 5.49e-58: 177: 93.38
+	Hs
		832357 MCM2_HUMAN (28-732): 0: 675: 30.09		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		832495 MCM2_HUMAN (28-732): 0: 675: 30.09		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		832369 MCM2_HUMAN (28-732): 0: 675: 30.09		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		708415 MCM4_HUMAN (6-724): 0: 672: 30.20		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		832541 MCM2_HUMAN (28-732): 0: 675: 30.09		H32_HUMAN (1-136): 6.5e-61: 185: 99.27
+	Hs
		708421 MCM4_HUMAN (6-724): 0: 672: 30.20		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Mm
		935446 MCM2_MOUSE (28-732): 0: 667: 30.09		H31_MOUSE (1-136): 2.8e-62: 188: 100.00
+	Mm
		952736 MCM2_MOUSE (28-732): 0: 667: 30.09		H33_MOUSE (1-136): 2.73e-61: 186: 96.32
+	Mm
		952250 MCM2_MOUSE (28-732): 0: 667: 30.09		H32_MOUSE (1-136): 6.5e-61: 185: 99.27
+	Sc
		667879 MCM5_YEAST (4-732): 0: 674: 46.34		H3_YEAST (1-136): 1.16e-55: 172: 88.97
+	Mm
		935450 Q3V122_MOUSE (27-730): 0: 655: 26.76		H31_MOUSE (1-136): 2.8e-62: 188: 100.00
+	Mm
		952743 Q3V122_MOUSE (27-730): 0: 655: 26.76		H33_MOUSE (1-136): 2.73e-61: 186: 96.32
+	Mm
		952257 Q3V122_MOUSE (27-730): 0: 655: 26.76		H32_MOUSE (1-136): 6.5e-61: 185: 99.27
+	Hs
		828172 MCM2_HUMAN (28-732): 0: 675: 30.09		CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00
+	Hs
		708398 MCM4_HUMAN (6-724): 0: 672: 30.20		CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00