Interactor 1: CCN2 (P29279)
CCN family member 2 (Cellular communication network factor 2) (Connective tissue growth factor) (Hypertrophic chondrocyte-specific protein 24) (Insulin-like growth factor-binding protein 8) (IBP-8) (IGF-binding protein 8) (IGFBP-8)
Gene: CCN2

Interactor 2: MMP14 (P50281)
Matrix metalloproteinase-14 (MMP-14) (EC 3.4.24.80) (MMP-X1) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP)
Gene: MMP14

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.501

The method score is based on:

Property Details
Experiments 15255181
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001525 - angiogenesis
GO:0005178 - integrin binding
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0030324 - lung development
and 2 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 349
Hs

1 582
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025