HitPredict

Interactor 1: EPHA2 (P29317)
Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)
Gene: EPHA2

Interactor 2: CTNA1 (P35221)
Catenin alpha-1 (Alpha E-catenin) (Cadherin-associated protein) (Renal carcinoma antigen NY-REN-13)
Gene: CTNNA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36976175
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0007155 - cell adhesion GO:0016477 - cell migration GO:0030027 - lamellipodium and 1 others more... GO:0045296 - cadherin binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 976 Hs			1 906
+	Hs
		764340 EPHA7_HUMAN (4-974): 0: 1120: 50.15		CTNA1_HUMAN (1-906): 0: 1080: 100.00
+	Hs
		764288 EPHA4_HUMAN (1-974): 0: 1110: 50.35		CTNA1_HUMAN (1-906): 0: 1080: 100.00
+	Hs
		684484 EPHA4_HUMAN (1-974): 0: 1110: 50.35		CTNA2_HUMAN (6-905): 0: 1044: 77.87
+	Rn
		580516 INSR_RAT (371-873): 1.87e-134: 440: 29.49		Q5U302_RAT (1-906): 0: 1062: 99.23
+	Hs
		710543 EPHA2_HUMAN (1-976): 0: 1124: 100.00		CTNL1_HUMAN (147-847): 1.84e-63: 230: 14.83
+	Hs
		463372 LYN_HUMAN (607-879): 2.07e-64: 228: 42.91		CTNA1_HUMAN (1-906): 0: 1080: 100.00
+	Hs
		463818 LYN_HUMAN (607-879): 2.07e-64: 228: 42.91		CTNL1_HUMAN (147-847): 1.84e-63: 230: 14.83