HitPredict

Interactor 1: MPK1 (P39745)
Mitogen-activated protein kinase mpk-1 (EC 2.7.11.24) (MAP kinase sur-1)
Gene: mpk-1

Interactor 2: NHR69 (P91829)
Nuclear hormone receptor family member nhr-69
Gene: nhr-69

Species: Caenorhabditis elegans

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.668

Property	Details
Experiments	12679813, 10615043, 14704431
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 444 Ce			1 373
+	Ce
		219826 MPK1_CAEEL (1-444): 4.5e-168: 481: 100.00		NHR64_CAEEL (6-361): 2.05e-99: 301: 41.48
+	Hs
		587121 MK01_HUMAN (82-427): 1.2e-150: 433: 79.77		RXRA_HUMAN (3-345): 2.52e-113: 339: 30.61
+	Hs
		587119 MK03_HUMAN (67-432): 1.45e-148: 429: 71.86		RXRA_HUMAN (3-345): 2.52e-113: 339: 30.61
+	Hs
		658827 MK01_HUMAN (82-427): 1.2e-150: 433: 79.77		HNF4A_HUMAN (2-371): 5.22e-111: 334: 36.49
+	Hs
		647494 MK03_HUMAN (67-432): 1.45e-148: 429: 71.86		HNF4A_HUMAN (2-371): 5.22e-111: 334: 36.49
+	Hs
		369038 MK01_HUMAN (82-427): 1.2e-150: 433: 79.77		ESR1_HUMAN (4-367): 1.79e-97: 303: 22.14
+	Hs
		659019 MK01_HUMAN (82-427): 1.2e-150: 433: 79.77		ESR2_HUMAN (6-372): 1.42e-93: 291: 22.14
+	Hs
		487905 MK01_HUMAN (82-427): 1.2e-150: 433: 79.77		RARA_HUMAN (2-344): 8.09e-93: 287: 24.42
+	Hs
		647642 MK03_HUMAN (67-432): 1.45e-148: 429: 71.86		ESR2_HUMAN (6-372): 1.42e-93: 291: 22.14
+	Hs
		611449 MK14_HUMAN (83-428): 2.77e-149: 430: 48.28		NR4A1_HUMAN (3-347): 3.11e-91: 287: 21.78
+	Hs
		658834 MK01_HUMAN (82-427): 1.2e-150: 433: 79.77		NR4A2_HUMAN (3-347): 1.71e-88: 280: 22.73
+	Hs
		647499 MK03_HUMAN (67-432): 1.45e-148: 429: 71.86		NR4A2_HUMAN (3-347): 1.71e-88: 280: 22.73
+	Mm
		521436 MK14_MOUSE (83-434): 4.42e-142: 411: 47.46		NR4A1_MOUSE (3-347): 3.97e-90: 284: 22.73