Interactor 1: URB1 (P34241)
Nucleolar pre-ribosomal-associated protein 1 (Unhealthy ribosome biogenesis protein 1)
Gene: URB1

Interactor 2: DBP6 (P53734)
ATP-dependent RNA helicase DBP6 (EC 3.6.4.13) (DEAD box protein 6)
Gene: DBP6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.748

The method score is based on:

Property Details
Experiments 25877921, 30169518, 15226434, 36018804, 37968396, unassigned1262, 16429126
Identification Methods two hybrid, affinity chromatography technology, pull down, proximity labelling technology, anti tag coimmunoprecipitation, validated two hybrid, two hybrid array, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 - maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0042273 - ribosomal large subunit biogenesis
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1764
Sc

1 629
+ Sc
+ Sc

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Last updated: 15 Jul 2024