Protein: USE1
Vesicle transport protein USE1 (Putative MAPK-activating protein PM26) (USE1-like protein) (p31)

Gene: USE1
Organism: Homo sapiens
Interactions: 155
UniProt ID: Q9NZ43

Gene Ontology (top 5):
GO:0005484 - SNAP receptor activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006890 - retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
GO:0007041 - lysosomal transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1452966

STX18
Syntaxin-18

6

1

Small-scale

0.736

High

1091995

SEC20
Vesicle transport protein SEC20

6

1

Small-scale

0.730

High

1358385

SCFD1
Sec1 family domain-containing protein 1

5

1

Small-scale

0.716

High

1391524

BSCL2
Seipin

4

2

High-throughput

0.693

High

1238619

RINT1
RAD50-interacting protein 1

5

0

Small-scale

0.683

High

60432

NBAS
NBAS subunit of NRZ tethering complex

4

0

Small-scale

0.667

High

211870

ZW10
Centromere/kinetochore protein zw10 homolog

4

0

Small-scale

0.667

High

189881

STX7
Syntaxin-7

3

7

High-throughput

0.667

High

1097907

STX5
Syntaxin-5

3

8

High-throughput

0.667

High

1294848

STX12
Syntaxin-12

3

7

High-throughput

0.667

High

1087316

STX4
Syntaxin-4

3

6

High-throughput

0.653

High

933065

SNAA
Alpha-soluble NSF attachment protein

4

4

High-throughput

0.638

High

230451

CREB3
Cyclic AMP-responsive element-binding protein 3

3

0

High-throughput

0.630

High

278572

VAMP4
Vesicle-associated membrane protein 4

2

3

High-throughput

0.628

High

280358

SC22B
Vesicle-trafficking protein SEC22b

2

5

High-throughput

0.628

High

331926

GOSR1
Golgi SNAP receptor complex member 1

2

1

High-throughput

0.628

High

1159647

STX1A
Syntaxin-1A

2

6

High-throughput

0.606

High

1406410

MGLL
Monoglyceride lipase

2

0

High-throughput

0.585

High

1142963

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

0

High-throughput

0.580

High

1328215

JAGN1
Protein jagunal homolog 1

2

0

High-throughput

0.580

High

1328816

TM86B
Lysoplasmalogenase TMEM86B

2

0

High-throughput

0.580

High

1410682

APOL2
Apolipoprotein L2

2

0

High-throughput

0.580

High

328752

VAMP5
Vesicle-associated membrane protein 5

2

4

High-throughput

0.574

High

951477

SC61B
Protein transport protein Sec61 subunit beta

2

0

High-throughput

0.559

High

1109077

AQP6
Aquaporin-6

2

1

High-throughput

0.553

High

160342

GOSR2
Golgi SNAP receptor complex member 2

1

4

High-throughput

0.536

High

180078

BET1
BET1 homolog

1

2

High-throughput

0.536

High

192332

YKT6
Synaptobrevin homolog YKT6

1

5

High-throughput

0.536

High

1100729

STX3
Syntaxin-3

1

6

High-throughput

0.536

High

1154770

VAMP3
Vesicle-associated membrane protein 3

1

4

High-throughput

0.536

High

1407050

SNAG
Gamma-soluble NSF attachment protein

1

4

High-throughput

0.536

High

1452967

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

1

4

High-throughput

0.536

High

1452972

STX8
Syntaxin-8

1

3

High-throughput

0.536

High

386307

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

1

High-throughput

0.535

High

117022

J3KQ12
Seipin

1

2

High-throughput

0.515

High

943142

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

1203817

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.513

High

1210125

SNP47
Synaptosomal-associated protein 47

1

0

High-throughput

0.513

High

1384226

LDAF1
Lipid droplet assembly factor 1

1

0

High-throughput

0.513

High

423332

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

374242

RASN
GTPase NRas

1

1

High-throughput

0.479

High

376024

RASK
GTPase KRas

1

1

High-throughput

0.479

High

466493

RHOC
Rho-related GTP-binding protein RhoC

1

3

High-throughput

0.479

High

581333

RAC2
Ras-related C3 botulinum toxin substrate 2

1

3

High-throughput

0.479

High

955681

CDC42
Cell division control protein 42 homolog

1

3

High-throughput

0.479

High

962562

RHOA
Transforming protein RhoA

1

3

High-throughput

0.479

High

1395969

DNJC1
DnaJ homolog subfamily C member 1

1

3

High-throughput

0.479

High

1431271

DJC25
DnaJ homolog subfamily C member 25

1

1

High-throughput

0.479

High

1452973

DJC16
DnaJ homolog subfamily C member 16

1

1

High-throughput

0.479

High

174128

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.458

High

417810

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

418475

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

630996

RAB4A
Ras-related protein Rab-4A

1

0

High-throughput

0.458

High

715814

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

847721

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.458

High

895115

EMD
Emerin

1

0

High-throughput

0.458

High

901620

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.458

High

904164

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

1027217

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.458

High

1058695

CKAP4
Cytoskeleton-associated protein 4

1

0

High-throughput

0.458

High

1111731

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.458

High

1125702

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

0

High-throughput

0.458

High

1249271

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1309905

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.458

High

1334039

DHB11
Estradiol 17-beta-dehydrogenase 11

1

0

High-throughput

0.458

High

1334598

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.458

High

1352380

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.458

High

1383123

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

1401245

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

1404246

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

1414482

DERL1
Derlin-1

1

0

High-throughput

0.458

High

1421164

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.458

High

1431772

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.458

High

1436341

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

1452707

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.458

High

1452965

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.458

High

214961

HNRPR
Heterogeneous nuclear ribonucleoprotein R

1

1

Small-scale

0.445

High

925761

SC24C
Protein transport protein Sec24C

1

1

Small-scale

0.445

High

1148953

SC23A
Protein transport protein Sec23A

1

1

Small-scale

0.445

High

1312077

DJC10
DnaJ homolog subfamily C member 10

1

1

Small-scale

0.445

High

1346808

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

2

High-throughput

0.445

High

710525

EPHA2
Ephrin type-A receptor 2

1

2

High-throughput

0.437

High

710906

EPHB2
Ephrin type-B receptor 2

1

2

High-throughput

0.437

High

932003

EPHB4
Ephrin type-B receptor 4

1

2

High-throughput

0.437

High

1452971

ALK
ALK tyrosine kinase receptor

1

1

High-throughput

0.437

High

658444

RS3
Small ribosomal subunit protein uS3

1

0

Small-scale

0.426

High

141682

DDX3X
ATP-dependent RNA helicase DDX3X

1

2

Small-scale

0.407

High

172238

HNRDL
Heterogeneous nuclear ribonucleoprotein D-like

1

7

Small-scale

0.407

High

485468

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

5

Small-scale

0.407

High

608770

DDX5
Probable ATP-dependent RNA helicase DDX5

1

1

Small-scale

0.407

High

650992

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

5

Small-scale

0.407

High

729136

HNRH3
Heterogeneous nuclear ribonucleoprotein H3

1

2

Small-scale

0.407

High

857192

NSF
Vesicle-fusing ATPase

1

1

Small-scale

0.407

High

909718

ROA3
Heterogeneous nuclear ribonucleoprotein A3

1

7

Small-scale

0.407

High

913073

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

2

Small-scale

0.407

High

1027808

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

1

Small-scale

0.407

High

1029045

TIAR
Nucleolysin TIAR

1

1

Small-scale

0.407

High

1096408

ROA0
Heterogeneous nuclear ribonucleoprotein A0

1

6

Small-scale

0.407

High

1120369

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

6

Small-scale

0.407

High

1251195

ZNT10
Calcium/manganese antiporter SLC30A10

1

2

High-throughput

0.407

High

1288054

PRP39
Pre-mRNA-processing factor 39

1

1

Small-scale

0.407

High

1293428

CARM1
Histone-arginine methyltransferase CARM1

1

1

Small-scale

0.407

High

1337988

ZNT7
Zinc transporter 7

1

2

High-throughput

0.407

High

1367812

TFG
Protein TFG

1

1

Small-scale

0.407

High

1399773

RBM14
RNA-binding protein 14

1

2

Small-scale

0.407

High

1406866

ROAA
Heterogeneous nuclear ribonucleoprotein A/B

1

6

Small-scale

0.407

High

1407920

ANM1
Protein arginine N-methyltransferase 1

1

1

Small-scale

0.407

High

1414350

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

1

Small-scale

0.407

High

1447131

DDX4
Probable ATP-dependent RNA helicase DDX4

1

2

Small-scale

0.407

High

60821

TYW5
tRNA wybutosine-synthesizing protein 5

3

0

High-throughput

0.347

High

1356295

SCFD2
Sec1 family domain-containing protein 2

3

0

High-throughput

0.347

High

1452968

CS025
UPF0449 protein C19orf25

3

0

High-throughput

0.347

High

1452974

PCDB7
Protocadherin beta-7

2

0

High-throughput

0.328

High

1210320

MF14B
Hippocampus abundant transcript-like protein 1

2

0

High-throughput

0.316

High

1238030

CCD70
Coiled-coil domain-containing protein 70

2

0

High-throughput

0.316

High

1417404

CABP8
Calcium-binding protein 8

2

0

High-throughput

0.316

High

1449776

CCM2L
Cerebral cavernous malformations 2 protein-like

2

0

High-throughput

0.316

High

1452308

SCN3B
Sodium channel regulatory subunit beta-3

2

0

High-throughput

0.316

High

572250

TRI27
Zinc finger protein RFP

1

0

High-throughput

0.299

High

894211

MEOX2
Homeobox protein MOX-2

1

0

High-throughput

0.299

High

194853

KCNN4
Intermediate conductance calcium-activated potassium channel protein 4

1

0

High-throughput

0.279

Low

437505

CASB
Beta-casein

1

0

High-throughput

0.279

Low

1130869

RRP5
Protein RRP5 homolog

1

0

High-throughput

0.279

Low

1273290

HS2ST
Heparan sulfate 2-O-sulfotransferase 1

1

0

High-throughput

0.279

Low

1410538

KXDL1
KxDL motif-containing protein 1

1

0

High-throughput

0.279

Low

1417823

PDIP3
Polymerase delta-interacting protein 3

1

0

High-throughput

0.279

Low

1429631

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.279

Low

1432434

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.279

Low

291568

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.249

Low

837877

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.249

Low

1005182

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1163433

CAH9
Carbonic anhydrase 9

1

0

High-throughput

0.249

Low

1323018

CXD3
Gap junction delta-3 protein

1

0

High-throughput

0.249

Low

1339208

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.249

Low

1434079

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1448028

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.249

Low

1448158

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.249

Low

1450113

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

1452964

TM216
Transmembrane protein 216

1

0

High-throughput

0.249

Low

1452969

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

476854

RSSA
Small ribosomal subunit protein uS2

1

0

Small-scale

0.232

Low

533019

CH60
60 kDa heat shock protein, mitochondrial

1

0

Small-scale

0.232

Low

550497

PABP1
Polyadenylate-binding protein 1

1

0

Small-scale

0.232

Low

667486

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.232

Low

877723

SL9A3
Sodium/hydrogen exchanger 3

1

0

High-throughput

0.232

Low

965919

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

0

Small-scale

0.232

Low

977844

ACTA
Actin, aortic smooth muscle

1

0

Small-scale

0.232

Low

1089583

ILF2
Interleukin enhancer-binding factor 2

1

0

Small-scale

0.232

Low

1236360

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.232

Low

1371080

ARHG2
Rho guanine nucleotide exchange factor 2

1

0

Small-scale

0.232

Low

1391110

TRM61
tRNA

1

0

Small-scale

0.232

Low

1411621

FSP1
Ferroptosis suppressor protein 1

1

0

Small-scale

0.232

Low

1446375

INO1
Inositol-3-phosphate synthase 1

1

0

Small-scale

0.232

Low

1452970

TRM6
tRNA

1

0

Small-scale

0.232

Low

1452975

NS1BP
Influenza virus NS1A-binding protein

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025