HitPredict

Interactor 1: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Interactor 2: DNJB8 (Q8NHS0)
DnaJ homolog subfamily B member 8
Gene: DNAJB8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33957083
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~HSP70
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 840 Hs			1 232
+	Hs
		636462 HSP74_HUMAN (1-840): 0: 993: 100.00		DNJB2_HUMAN (1-222): 1.87e-73: 227: 48.44
+	Hs
		320815 HS74L_HUMAN (1-840): 0: 959: 63.21		DNJB2_HUMAN (1-222): 1.87e-73: 227: 48.44
+	Hs
		258129 HS105_HUMAN (1-840): 0: 938: 62.95		DNJB6_HUMAN (1-222): 5.48e-72: 223: 58.87
+	Hs
		714326 HSP74_HUMAN (1-840): 0: 993: 100.00		DNJB3_HUMAN (1-141): 8.56e-53: 168: 53.90
+	Hs
		714320 HSP74_HUMAN (1-840): 0: 993: 100.00		DJB14_HUMAN (2-149): 5.94e-45: 155: 37.01
+	Hs
		279281 HSP74_HUMAN (1-840): 0: 993: 100.00		DNJB5_HUMAN (2-163): 4.82e-43: 150: 35.80
+	Hs
		636257 HSP74_HUMAN (1-840): 0: 993: 100.00		DNJB1_HUMAN (2-161): 2.92e-42: 147: 33.74
+	Hs
		714449 HSP74_HUMAN (1-840): 0: 993: 100.00		DNJB4_HUMAN (2-159): 2.36e-41: 145: 37.98
+	Hs
		320814 HS74L_HUMAN (1-840): 0: 959: 63.21		DNJB1_HUMAN (2-161): 2.92e-42: 147: 33.74
+	Hs
		681540 HS105_HUMAN (1-840): 0: 938: 62.95		DNJA1_HUMAN (4-224): 2.87e-48: 164: 27.93
+	Hs
		279330 HS105_HUMAN (1-840): 0: 938: 62.95		DNJB5_HUMAN (2-163): 4.82e-43: 150: 35.80
+	Hs
		636386 HS105_HUMAN (1-840): 0: 938: 62.95		DNJB1_HUMAN (2-161): 2.92e-42: 147: 33.74
+	Hs
		1267773 HS105_HUMAN (1-840): 0: 938: 62.95		DNJB4_HUMAN (2-159): 2.36e-41: 145: 37.98
+	Hs
		1123860 HS105_HUMAN (1-840): 0: 938: 62.95		Q59E89_HUMAN (2-159): 8.33e-41: 144: 37.98
+	Dm
		1096122 Q9VUC1_DROME (1-840): 0: 821: 42.10		DNAJ1_DROME (2-219): 1.51e-50: 169: 30.09
+	Ce
		450534 HSP1_CAEEL (2-603): 0: 811: 31.48		Q20774_CAEEL (3-110): 8.87e-21: 90.5: 47.71
+	Sc
		633056 HSP79_YEAST (5-697): 5.63e-139: 429: 38.18		MAS5_YEAST (4-224): 2.94e-48: 165: 29.41
+	Sc
		633055 HSP7F_YEAST (5-697): 5.7e-137: 424: 37.61		MAS5_YEAST (4-224): 2.94e-48: 165: 29.41
+	Hs
		257901 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		DNJB6_HUMAN (1-222): 5.48e-72: 223: 58.87
+	Hs
		279272 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		DNJB5_HUMAN (2-163): 4.82e-43: 150: 35.80